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A dosage of 1 g intravenous acetaminophen every six hours yields serum concentrations below 10 µg/mL for critically ill multiple-trauma patients

1-g IV Acetaminophen Dose May Be Insufficient in Multiple Trauma

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Administration at recommended dosage yields serum concentrations below 10 µg/mL
Staff burnout in neonatal intensive care units is most prevalent in units with high patient volume and electronic health records

High-Volume NICUs See More Staff Burnout

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Burnout in NICUs may disproportionately affect nurses
Behaviors that residents value in intensive care unit attending physicians include enjoyment of teaching and treatment of patients

Residents Rate Enjoyment of Teaching As Key for ICU Doctors

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Behaviors of attending physicians rated as important include empathy to patients, ability to explain
A questionnaire-based approach seems to be valid for identifying adults in the intensive care unit with a frailty phenotype

Questionnaire-Based Approach Valid for Identifying Frailty

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Frailty phenotype with three or more markers predicts death or increased disability at six months
Early

Early, Goal-Directed Therapy No Benefit in Septic Shock

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Patient-level meta-analysis shows similar mortality at 90 days for EGDT and usual care
For patients with sepsis requiring mechanical ventilation

DEX Doesn’t Reduce Mortality in Those With Sepsis on Ventilator

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Dexmedetomidine also did not reduce ventilator-free days for sepsis patients on mechanical ventilation
For patients with hypoxemia after cardiac surgery

Intensive Strategy Addresses Hypoxemia After Cardiac Surgery

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Intensive alveolar recruitment strategy linked to less severe pulmonary complications after cardiac sx
For patients in septic shock

Thiamine May Reduce Progression to Renal Replacement Therapy

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Findings for patients in septic shock
Critical care nurses who experience unsuccessful cardiopulmonary resuscitation may experience moderate levels of postcode stress and posttraumatic stress disorder symptoms

Postcode Stress, PTSD Seen After Unsuccessful Resuscitation

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Critical care nurses show moderate levels of stress, PTSD after unsuccessful CPR
Admission to the intensive care unit (ICU) is not associated with a survival benefit for patients with uncertain ICU needs hospitalized with exacerbation of chronic obstructive pulmonary disease

ICU Appears Overused for Some Patients With Heart, Lung Disease

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Researchers find no difference in mortality rates, but higher costs for intensive care for some patients