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For older Medicare beneficiaries with type 2 diabetes mellitus

Early Insulin Initiation Beneficial in Seniors With T2DM

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Benefits for early insulin initiation without increasing risk of hypoglycemia, health care costs
In a small

High-Dose Oral Insulin Promising for Prevention of T1DM

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Daily capsules trigger protective immune response in high-risk children
Dietary n-3 polyunsaturated fatty acids

Effects of n-3 PUFAs on Insulin Sensitivity Unclear

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No effect on peripheral insulin sensitivity; modest improvement in hepatic insulin sensitivity
The inclusion of peanuts as part of a high-fat meal improves the postprandial triglyceride response and preserves endothelial function

Eating Peanuts Aids Postprandial Triglyceride Response

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Preserved endothelial function seen after consumption of high-fat meal containing peanuts
Skeletal muscle phosphatase and tensin homolog deleted on chromosome 10 regulates insulin resistance in a sex-specific manner

PTEN Regulation of Insulin Resistance Is Sex Specific

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Women have downregulation of PTEN gene expression, upregulation of PTEN protein phosphorylation
Modern insulin pump technologies could be further improved by adopting a more rigorous

Joint European, U.S. Statement Issued on Insulin Pump Safety

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Regulators should require more from manufacturing companies; more data needed on long-term use
Despite the widespread availability of generic drugs

Incremental Innovation Impedes Progress on Generic Insulin

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Insulin has evolved through incremental improvements, with innovations in safety, efficacy
Salsalate increases insulin concentrations by decreasing metabolic clearance of insulin

Salicylates Reduce Metabolic Clearance of Insulin

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Increased insulin levels not caused by increased insulin secretion rate
After menopause

Insulin Resistance Ups Breast Cancer Risk Regardless of BMI

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Study of postmenopausal women suggests hormone levels matter more than excess weight