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Use of anabolic androgenic steroids may lead to insulin resistance

Misuse of Anabolic Steroids Linked to Insulin Resistance

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Effect may be mediated by increased visceral adipose tissue as primary metabolically active fat tissue
Long-term exposure to air pollution is associated with insulin resistance among the general population

Long-Term Exposure to Air Pollution Ups Insulin Resistance

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Effect estimates much larger and highly significant for individuals with prediabetes
For obese patients without diabetes

Rapid Improvement in Insulin Sensitivity With Bariatric Surgery

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Improvements in hepatic insulin sensitivity, endogenous glucose production, lipolysis
Dry-heat cooking that produces advanced glycation end products may increase the risk of type 2 diabetes

Avoiding Dry-Cooked Foods May Help Protect Against T2DM

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Researchers suggest steaming, poaching, and stewing for better health
Dapagliflozin improves insulin sensitivity and increases lipid oxidation and plasma ketone concentration in patients with type 2 diabetes mellitus (T2DM)

Dapagliflozin Improves Insulin Sensitivity in Type 2 Diabetes

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Decrease in basal glucose oxidation; increases in lipid oxidation, plasma ketone concentration
Liraglutide added to capped insulin is associated with reductions in glycated hemoglobin

Liraglutide Added to Capped Insulin Reduces Hemoglobin A1c

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Liraglutide also significantly reduces mean body weight, daily insulin dose; increases quality of life
Inhibiting the sympathetic nervous system by renal denervation improves insulin sensitivity in obese canines

Renal Denervation Ups Insulin Sensitivity in Preclinical Model

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Bilateral renal denervation completely normalizes hepatic insulin sensitivity in obese canines
C-peptide responses to mixed-meal tolerance tests are reliable surrogates of insulin secretion

C-Peptide Responses Reliable Surrogates of Insulin Secretion

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Expected inverse relationships between C-peptide and HbA1c, insulin dose vary over time, with age
Two novel loci have been identified that are associated with insulin sensitivity

Study IDs Two Novel Loci Linked to Insulin Sensitivity

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Associations for BCL2 and FAM19A2 were independent of known cardiometabolic loci
For East Asian patients with type 2 diabetes

50 Percent Insulin Lispro/Insulin Lispro Protamine Efficacious

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More effective than LM25 in certain dietary conditions, including with increased carbohydrate