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Insulin resistance assessed by homeostasis model assessment index correlates with the risk of hepatocellular carcinoma in patients with chronic hepatitis B virus infection

HOMA2-IR Tied to Hepatocellular Carcinoma Risk in Hepatitis B

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HOMA2-IR independently linked to HCC in patients without overt metabolic abnormalities
Hospital patients with hypoglycemia may be at increased mortality risk

Mortality Risk Up for Hospital Patients With Hypoglycemia

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Hypoglycemia, either with insulin or spontaneous, linked to increased short- and long-term mortality
In obese canines

Bilateral Renal Denervation Normalizes Insulin Sensitivity

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Normalization seen in obese canines, by reducing hepatic gluconeogenic genes, including G6Pase
A brief

Educational Intervention Aids Problematic Hypoglycemia

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Nonsignificant reduction in hypoglycemia episodes; significant improvement in hypoglycemia awareness
For patients with type 2 diabetes mellitus

Statins Offset Insulin-Related Cancer Risk in T2DM

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Risks of cancer reduced with statins; greater risk reduction in those not receiving antihyperglycemic tx
Postmenopausal obese women who lose weight eating a high-protein diet may not experience any improvements in insulin sensitivity

High-Protein Diet Doesn’t Improve Insulin Sensitivity

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Findings in postmenopausal obese women without diabetes
For patients with inadequately controlled

Insulin Glargine, Lixisenatide Combo Beneficial in T2DM

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Improved achievement of glycemic targets, reduced body weight
Use of anabolic androgenic steroids may lead to insulin resistance

Misuse of Anabolic Steroids Linked to Insulin Resistance

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Effect may be mediated by increased visceral adipose tissue as primary metabolically active fat tissue
Long-term exposure to air pollution is associated with insulin resistance among the general population

Long-Term Exposure to Air Pollution Ups Insulin Resistance

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Effect estimates much larger and highly significant for individuals with prediabetes
For obese patients without diabetes

Rapid Improvement in Insulin Sensitivity With Bariatric Surgery

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Improvements in hepatic insulin sensitivity, endogenous glucose production, lipolysis