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Cardiometabolic risk and homeostatic model assessment of insulin resistance increase with increasing body mass index categories among children

Cardiometabolic Risk, HOMA-IR Up With Increasing BMI in Young

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Cardiorespiratory fitness cuts cardiometabolic risk score as BMI categories rise in children
Cardiovascular outcomes in patients with diabetes are not explained by insulin resistance

Insulin Dose Not Tied to Cardiovascular Outcomes

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Similar findings among individuals with diabetes able to achieve normoglycemia
Intestinal glucose stimulation has an anti-incretin effect

Intestinal Glucose Stimulation Has Anti-Incretin Effect

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Insulin sensitivity lower during oral versus IV glucose administration; difference amplified in obese
A cognitive test involving animal name recall can predict which elderly patients succeed in mastering an insulin self-injection technique within one week

Cognitive Test Predicts Elderly Insulin Injection Success

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Number of animal names recalled in one minute was the most useful indicator
Adults with type 2 diabetes receiving multiple daily insulin injections randomized to continuous glucose monitoring have improved glycemic control versus usual care

In T2D, Glycemic Control Up With Continuous Glucose Monitoring

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Improved glycemic control with CGM for patients with T2DM receiving multiple insulin injections daily
For patients with type 1 or type 2 diabetes

Insulin Degludec Linked to Reduced Rate of Hypoglycemia

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Reduced rate of hypoglycemic episodes among patients with type 1 diabetes, type 2 diabetes
For children

Genetic, Environmental Exposure Tied to Islet Autoantibodies

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Link for male sex; father, sibling as diabetic proband; weight at 12 months with insulin autoantibodies
Patients with remaining endogenous β-cell function after a decade of living with type 1 diabetes tend to have much higher levels of interleukin-35 than other patients with long-standing type 1 diabetes

T1DM Patients With Active β-Cell Function Differ Immunologically

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Findings for patients with remaining endogenous β-cell function after 10 or more years of T1DM
Among high-risk patients with type 2 diabetes

ADA: Degludec Noninferior for Cardiovascular Events in T2DM

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Noninferior to glargine for incidence of major cardiovascular events in high-risk patients with T2DM
For most patients with non-insulin-treated type 2 diabetes

ADA: Glucose Self-Monitoring Often Lacks Benefit in T2DM

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No significant improvements in hemoglobin A1c levels, HRQOL seen in non-insulin-treated cases