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Cardiovascular outcomes in patients with diabetes are not explained by insulin resistance

Insulin Dose Not Tied to Cardiovascular Outcomes

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Similar findings among individuals with diabetes able to achieve normoglycemia
Intestinal glucose stimulation has an anti-incretin effect

Intestinal Glucose Stimulation Has Anti-Incretin Effect

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Insulin sensitivity lower during oral versus IV glucose administration; difference amplified in obese
A cognitive test involving animal name recall can predict which elderly patients succeed in mastering an insulin self-injection technique within one week

Cognitive Test Predicts Elderly Insulin Injection Success

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Number of animal names recalled in one minute was the most useful indicator
Adults with type 2 diabetes receiving multiple daily insulin injections randomized to continuous glucose monitoring have improved glycemic control versus usual care

In T2D, Glycemic Control Up With Continuous Glucose Monitoring

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Improved glycemic control with CGM for patients with T2DM receiving multiple insulin injections daily
For patients with type 1 or type 2 diabetes

Insulin Degludec Linked to Reduced Rate of Hypoglycemia

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Reduced rate of hypoglycemic episodes among patients with type 1 diabetes, type 2 diabetes
For children

Genetic, Environmental Exposure Tied to Islet Autoantibodies

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Link for male sex; father, sibling as diabetic proband; weight at 12 months with insulin autoantibodies
Patients with remaining endogenous β-cell function after a decade of living with type 1 diabetes tend to have much higher levels of interleukin-35 than other patients with long-standing type 1 diabetes

T1DM Patients With Active β-Cell Function Differ Immunologically

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Findings for patients with remaining endogenous β-cell function after 10 or more years of T1DM
Among high-risk patients with type 2 diabetes

ADA: Degludec Noninferior for Cardiovascular Events in T2DM

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Noninferior to glargine for incidence of major cardiovascular events in high-risk patients with T2DM
For most patients with non-insulin-treated type 2 diabetes

ADA: Glucose Self-Monitoring Often Lacks Benefit in T2DM

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No significant improvements in hemoglobin A1c levels, HRQOL seen in non-insulin-treated cases
For obese adults

Breaking Up Sedentary Time With Upper Body Activity Beneficial

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Short bouts of arm ergometry linked to reductions in mean blood glucose, insulin iAUC in obese individuals