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The increasing cost of insulin is potentially exposing those with diabetes to serious health consequences

Increasing Cost of Insulin Has Serious Health Consequences

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Lowest-priced insulin required to safely, effectively achieve treatment goals should be prescribed
Basal insulin analogues for type 2 diabetes mellitus do not substantially differ in their glucose-lowering effect

Basal Insulin Analogues Similar for Glucose Lowering

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Slight differences in risk for nocturnal hypoglycemia or weight gain exist
Initiation of a basal insulin analog versus human neutral protamine Hagedorn insulin is not associated with reduction in the risk of hypoglycemia-related emergency department visits or hospital admissions

Basal Insulin Analogs Don’t Cut Hypoglycemia-Linked ER Visits

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No reduced risk of hypoglycemia-linked ER visits, admissions for basal insulin analog vs. NPH insulin
The endogenous circadian system

Circadian System, Misalignment Have Distinct Impact on Insulin

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Circadian misalignment affects insulin sensitivity and insulin secretion in humans
An oral insulin formulation has been developed using choline and geranate ionic liquid

Oral Insulin Choline, Geranate Ionic Liquid Shows Promise

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Significant, sustained decrease in blood glucose levels with low insulin doses of 3 to 10 U/kg
For older adults

Insulin Glargine 300 Safe, Effective in Seniors With T2DM

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Significantly lower annualized rates of documented symptomatic hypoglycemia than Gla-100
Use of an automated

ADA: Closed-Loop Insulin Improves Glycemic Control

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Better glycemic control than conventional subcutaneous insulin therapy in patients with T2DM
U.S. officials need to take action to control spiking insulin prices

AMA: Federal Government Must Tackle Rising Insulin Prices

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Agencies should monitor pricing, market competition, and take any necessary enforcement measures
In obese subjects with and without type 2 diabetes mellitus

Oxyntomodulin Augments Glucose Homeostasis

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OXM effects seen in obese patients with and without T2DM; comparable effects to liraglutide in T2DM
For pregnant women with type 1 diabetes

Closed-Loop Insulin Delivery Promising in T1DM Pregnancy

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Comparable glucose control, less hypoglycemia vs. sensor-augmented pump tx in pregnant women