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Tag: Immunotherapy

Hyperimmune Globulin Does Not Prevent Congenital CMV Infection

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Cytomegalovirus hyperimmune globulin does not lower incidence of composite of congenital CMV infection, perinatal death in offspring

Immunomodulation With IVIG, Glucocorticoids Examined in MIS-C

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Early outcomes of two large observational studies show mixed results for the efficacy of immunomodulation with IVIG, glucocorticoids, or both

VTE Risk High in Cancer Patients Receiving Immune Checkpoint Inhibitors

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History of VTE predicts VTE occurrence; VTE occurrence linked to increased mortality

FDA Approves Immunotherapy for dMMR Endometrial Cancer

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Jemperli approved for dMMR endometrial cancer that progressed after platinum-containing chemotherapy treatment

Cutaneous AEs Linked to Immune Checkpoint Inhibitor Therapy

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Cutaneous immune-related adverse events seen in 25 percent of cancer patients initiating ICI therapy with median onset time of 113 days

Chronic Adverse Effects From Anti-PD-1 Immunotherapies Common

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About 43 percent of patients who receive anti-PD1 therapy for advanced melanoma have chronic immune-related adverse effects

Broadly Neutralizing Antibodies Do Not Prevent Overall HIV-1 Acquisition

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Analysis of pooled data from proof-of-concept trials shows bnAb VRC01 does reduce incidence of infection with VRC01-sensitive isolates

Early Immunologic Biomarker Predicts Renal Allograft Outcomes

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Ratio of IL-10/TNFα produced by T1B three months after renal transplantation predicts clinical, subclinical rejection during first year

Fecal Transplant May Counter Anti-PD-1 Resistance in Melanoma

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FMT plus anti-PD-1 therapy may change gut microbiome and help overcome drug resistance in some patients with advanced melanoma

SARS-CoV-2 Infection Rate Low in Patients Receiving Antitumor Therapy

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Less than 1 percent of patients receiving antitumor treatment between Jan. 15 and May 4, 2020, developed COVID-19