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Tag: Immunotherapy

AACR: Adjuvant Atezolizumab + Bevacizumab Beneficial in Liver Cancer

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Increased recurrence-free survival seen for patients with high-risk HCC following resection or ablation

Interferon Alfa-2b Effective for Low-Grade Lymphomatoid Granulomatosis

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61 percent of patients had complete response to interferon alfa-2b; patients with high-grade disease showed expected response to chemo

Neoadjuvant, Adjuvant Pembrolizumab Beneficial in Resectable Melanoma

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Event-free survival longer for those receiving neoadjuvant and adjuvant pembrolizumab versus adjuvant pembrolizumab only

Targeted Therapies Seem Beneficial for Immune Checkpoint Inhibitor-Related Myotoxicity

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Myotoxicity-related fatality rate 3.4 percent after institution of screening coupled with active ventilation, treatment

PD-1 Inhibitor Treatment Effective for Localized Mismatch Repair-Deficient CRC

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84.9 percent of 73 patients achieved objective response, including 23.3 percent with complete response

Oral Immunotherapy With Boiled Then Roasted Peanuts Feasible

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Sequential approach is feasible and safe for peanut allergy, with very low frequency of rescue epinephrine use

QOL Up With Pembrolizumab Versus Ipilimumab, HDI in Resected Melanoma

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Quality of life favored the pembrolizumab arm versus standard-of-care arm receiving ipilimumab, high-dose interferon α 2b

Treatment-Related Adverse Events of Antibody Drug Conjugates Identified

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Overall incidence of treatment-related adverse events was 91.2 percent and included lymphopenia, nausea, neutropenia

Treatment Sequence Studied for Advanced BRAF-Mutant Melanoma

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Two-year overall survival higher for those initiating treatment with combo nivolumab/ipilimumab versus dual BRAF/MEK inhibition

Adjuvant Nivolumab + Ipilimumab Lacks Efficacy for Localized RCC

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Trial did not meet primary efficacy end point of disease-free survival in patients with localized RCC at high risk for postnephrectomy relapse