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Tag: Immunotherapy

Adverse events for immune checkpoint inhibitors used to treat non-small cell lung cancer may be more common in real-world settings than reported in the clinical trials that led to U.S. Food and Drug Administration approvals

Immunotherapy Side Effects May Be More Common Than Thought

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Higher rates of adverse events observed for immune checkpoint inhibitors in real-world settings
Patients with peanut allergy who received oral immunotherapy

ACAAI: Oral Immunotherapy Is Protective in Peanut Allergy

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More patients receiving AR101 able to ingest ≥600 mg peanut protein without dose-limiting symptoms
For patients with metastatic triple-negative breast cancer

Chemoimmunotherapy Ups Survival in Triple-Negative Breast Cancer

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Atezolizumab plus nab-paclitaxel prolongs progression-free survival in metastatic disease
A single checkpoint inhibitor can be used to successfully treat two simultaneous types of primary cancer in a patient with Lynch syndrome

Single Agent Treats Two Cancers With Same Genetic Cause

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Pembrolizumab treated colon cancer, intrahepatic cholangiocarcinoma in patient with Lynch syndrome
Checkpoint blockade immunotherapy is associated with significant increases in overall survival in a real-world population of patients undergoing treatment for melanoma brain metastases

Novel Immunotherapy May Up Survival in Melanoma Brain Mets

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Findings in patients receiving checkpoint blockade immunotherapy for melanoma brain metastases
A new immunotherapy appears to be well tolerated and possibly of benefit in patients with amyotrophic lateral sclerosis

Immunotherapy Promising for Slowing Progression of ALS

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Positive results seen for autologous infusions of expanded regulatory T lymphocytes in three patients
A highly personalized therapy targeting multiple tumor antigens shows promise for metastatic breast cancer

Personalized Therapy Promising in Metastatic Breast Cancer

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Adaptive transfer of mutant-protein-specific tumor-infiltrating lymphocytes leads to disease regression
For patients with advanced cancers

Immune Checkpoint Inhibitor Efficacy Varies by Sex

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Magnitude of benefit of immune checkpoint inhibitors sex-dependent for patients with advanced cancers
Patients receiving immunotherapy with antiprogrammed cell death protein-1 and antiprogrammed cell death ligand-1 monoclonal antibodies may develop uveal effusion

Uveal Effusion Reported After Initiation of Anti-PD-1, -PD-L1

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Case series IDs three patients who developed uveal effusion within one to two months of initiating tx
Gemcitabine and cisplatin plus ipilimumab is associated with a 69 percent objective response rate and 61 percent one-year overall survival for patients with metastatic urothelial cancer

Chemo, Immunotherapy Feasible in Metastatic Bladder Cancer

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One-year overall survival of 61 percent for gemcitabine and cisplatin plus ipilimumab