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Tag: Immunotherapy

Black Patients Have Similar Immune Checkpoint Inhibitor Effectiveness, Lower Toxicity

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Black patients have longer time to treatment discontinuation, similar time to next treatment, slightly improved overall survival than White patients

Entinostat + Nivolumab Yields Durable Results in Some Pancreatic Cancer Patients

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Primary end point not met, but small subset of advanced pancreatic ductal adenocarcinoma patients showed durable responses

Adding Pembrolizumab Ups Survival in Stage III Undifferentiated Sarcoma

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Benefit seen for stage III undifferentiated pleomorphic sarcoma or dedifferentiated or pleomorphic liposarcoma of the extremity and limb girdles

ChemoRT Then Immunochemotherapy Then Surgery Promising in Unresectable Esophageal Cancer

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One-year progression-free survival, overall survival was 79.4, 89.6 percent; significantly longer survival seen in patients who achieved resectability

Tusamitamab Ravtansine Does Not Extend Survival With Nonsquamous NSCLC

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Findings seen in patients previously treated with platinum-based chemotherapy and immunotherapy whose tumors highly expressed CEACAM5

Perioperative Nivolumab Beneficial for Resectable NSCLC

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Perioperative nivolumab showed event-free survival benefit from time of surgery compared with neoadjuvant nivolumab

Socioeconomic Disparities Impact Immunotherapy Use in Urologic Cancers

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Disparities seen based on income, education, and insurance status for both advanced kidney, bladder cancer

Outcomes Similar for Neoadjuvant ICI-Based Therapy, Upfront Surgery for Liver Cancer

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Rates of margin-negative resection and recurrence-free survival similar for neoadjuvant immunotherapy, surgery patients

Acceptable Liver Transplant Outcomes Seen After ICI Therapy for Liver Cancer

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Age and immune checkpoint inhibitor washout time inversely linked to allograft rejection; survival no different with, without allograft rejection

Gene Expression Signature Predicts Immune-Related Adverse Events in Melanoma Patients

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Gene expression signature predicts irAEs in melanoma patients treated with ipilimumab/nivolumab