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The U.S. Food and Drug Administration on Monday approved Gamifant (emapalumab-lzsg) for the treatment of primary hemophagocytic lymphohistiocytosis (HLH) in pediatric (as young as newborn) and adult patients who have refractory

FDA Approves Drug to Treat Rare Immune Disease

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Gamifant first drug to be approved specifically for primary hemophagocytic lymphohistiocytosis
Following quadrivalent human papillomavirus vaccination

No Higher Risk of Autoimmune Disorders After HPV4 Vaccination

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Girls 12 to 17 have no increased risk of autoimmune disorders seven to 60 days after vaccination
In a case report published online June 18 in BMJ Case Reports

Tattoo-Linked Complications ID’d in Immunosuppressed Female

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Inflammatory myopathy identified in woman with cystic fibrosis on long-term immunosuppressants
Transcription factors seem to operate across gene loci

TFs Operate Across Gene Loci Within Disease Phenotypes

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Epstein-Barr virus EBNA2 protein binds to multiple loci of genome, increasing risk of 7 serious diseases
Stem cell transplant may be an effective treatment for systemic sclerosis

Stem Cell Transplant May Be Effective for Systemic Sclerosis

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Small study shows improvements in management of cutaneous, organ manifestations
Although patients with pre-existing autoimmune disease who receive checkpoint inhibitors (CPIs) are at risk for exacerbation of their disease

Immune-Related Adverse Events Up With Checkpoint Inhibitors

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Most patients with cancer, autoimmune disease have improvement in events without discontinuing therapy
New classification criteria have been developed for idiopathic inflammatory myopathies

Criteria Developed for Idiopathic Inflammatory Myopathies

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Classification criteria developed from rheumatology, dermatology, neurology, pediatric clinic data

October 2017 Briefing – Rheumatology

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Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for October 2017. This roundup includes the latest...
Most patients with immunoglobulin G subclass 4-related disease have increased levels of immunoglobulin E

Increases in IgE, Eosinophils, Mast Cells Can ID IgG4-RD

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Levels of IgE at diagnosis may be able to identify patients with IgG4-related disease, disease relapse

European League Against Rheumatism, June 14-17

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The European League Against Rheumatism 2017 Annual European Congress of Rheumatology The annual meeting of the European League Against Rheumatism was held from...