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Tag: Hormones: Thyroid

Thyrotoxicosis Linked to Risk for Incident Cognitive Disorder

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Exogenous thyrotoxicosis remained a significant risk factor for cognitive disorders when stratified by cause and severity

ENDO: Common Meds Interfere With TFTs in Older Adults on Thyroid Hormone

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Almost one-third of older adults on thyroid replacement therapy take at least one medication that interferes with thyroid function tests

Thyroid dysfunction in patients with psoriasis may be associated with inflammation caused by psoriasis

Inflammation Tied to Thyroid Dysfunction With Psoriasis

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Prevalence of thyroid dysfunction high with generalized pustular, erythrodermic psoriasis
Blood iodine concentrations in newborns do not vary for infants with or without congenital hypothyroidism

Newborn Iodine Status Not Tied to Congenital Hypothyroidism

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But among infants treated in neonatal ICU, cases had significantly higher blood iodine levels than controls
Synthetic levothyroxine is associated with an increased risk for death among older adults

ENDO: Thyroid Hormone Use May Up Mortality Risk in Older Adults

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Increased risk for death seen for visits on LT4 versus those with isolated elevated TSH who were untreated
Hypothyroidism is significantly associated with increased all-cause mortality

Overt Hypothyroidism May Up All-Cause Mortality in the Elderly

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However, no association seen between hypothyroidism and cardiovascular mortality
Cardiovascular event rates are similar for patients with newly treated hypothyroidism receiving generic and brand levothyroxine

Similar CV Event Rates Seen for Generic, Brand Levothyroxine

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Event rates did not differ for atrial fibrillation, myocardial infarction, congestive heart failure, stroke
Thyroid hormones are not recommended for adults with subclinical hypothyroidism

Thyroid Hormones Not Endorsed for Subclinical Hypothyroidism

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Almost all adults with SCH would not benefit from treatment with thyroid hormones
For euthyroid women with thyroid peroxidase antibodies and a history of miscarriage or infertility

ENDO: Levothyroxine Does Not Up Fertility in Women With TPO Ab

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Live-birth rate did not increase for euthyroid women with thyroid peroxidase antibodies before conception
Thyroid hormone therapy is not associated with improvements in general quality of life or thyroid-related symptoms in non-pregnant adults with subclinical hypothyroidism

Hormone Therapy Not Beneficial in Subclinical Hypothyroidism

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No benefit regarding quality of life or thyroid-related symptoms found for thyroid hormone therapy