Tag: Hormone Replacement Therapy
Type and Timing of Menopausal HRT Affect Risk for Breast Cancer
Some excess risk persists for >10 years after ceasing therapy; magnitude varies with duration of use
Hormone Tx Not Tied to Change in Muscle Mass in Older Women
No significant beneficial or detrimental association seen in postmenopausal women
Premature Ovarian Insufficiency Tied to Poor Sleep Quality
Patients take longer to fall asleep, use more sleep aids, have more fatigue
Long-Term Systemic Hormone Therapy May Up Alzheimer Risk
Risk increases associated with hormone therapy exposure over 10 years in women <60 years at initiation
Cardiovascular Risk Increased During Gender Transition
Transwomen had higher incidence of strokes, VTEs than reference men and women
Prevalence of Knee OA Lower With Menopausal Hormone Therapy
Odds ratio for knee osteoarthritis was 0.7 in MHT group versus non-MHT group in multivariable model
Menopausal Hormone Tx Use Down Post-WHI Recommendations
But large declines seen in subgroups for whom MHT is recommended, including younger women
Transdermal HRT Not Linked to Increased Risk for VTE
But oral estrogen-only and combined hormone replacement tx tied to venous thromboembolism risk
Menopausal Hormone Therapy Linked to Reduced Abdominal Fat
No residual effect for past users, including early discontinuers of menopause hormone treatment
Hormone Therapy May Impact Brain Structure, Cognition
But 3 years after menopausal HT, change in brain volumes not significantly different from placebo
