Tag: Hormone Replacement Therapy
Long-Term Systemic Hormone Therapy May Up Alzheimer Risk
Risk increases associated with hormone therapy exposure over 10 years in women <60 years at initiation
Cardiovascular Risk Increased During Gender Transition
Transwomen had higher incidence of strokes, VTEs than reference men and women
Prevalence of Knee OA Lower With Menopausal Hormone Therapy
Odds ratio for knee osteoarthritis was 0.7 in MHT group versus non-MHT group in multivariable model
Menopausal Hormone Tx Use Down Post-WHI Recommendations
But large declines seen in subgroups for whom MHT is recommended, including younger women
Transdermal HRT Not Linked to Increased Risk for VTE
But oral estrogen-only and combined hormone replacement tx tied to venous thromboembolism risk
Menopausal Hormone Therapy Linked to Reduced Abdominal Fat
No residual effect for past users, including early discontinuers of menopause hormone treatment
Hormone Therapy May Impact Brain Structure, Cognition
But 3 years after menopausal HT, change in brain volumes not significantly different from placebo
Menopausal Hormone Therapy Tied to Less Pronounced Kyphosis
Continuous and remote past HT users had less kyphosis in minimally-, fully-adjusted models
USPSTF Recommends Against Hormone Tx Post Menopause
Benefits do not outweigh harms of using hormone therapy for prevention of chronic conditions
Hormone Therapy in Menopause Not Tied to Increased Mortality
Findings based on long-term follow up of both all-cause, cause-specific deaths