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Tag: Herpes Zoster (Shingles)

Live Attenuated Zoster Vaccine Safe for Patients Receiving TNF Inhibitors

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No cases of varicella infection found; cumulative incidence of varicella infection or shingles was 0 percent

From 2008 to 2018

2008 to 2018 Saw Increase in Shingles Vaccination in Over 60s

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Women equally as likely as men to have received vaccine; coverage highest for non-poor, those with higher education
Vaccination with zoster vaccine live is associated with a reduced risk for stroke among older adults

ASA: Herpes Zoster Vaccine May Reduce Risk for Stroke

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Risk significantly reduced for stroke events, acute ischemic strokes, hemorrhagic strokes in older adults
The relative incidence of shingles is lower in adults after exposure to a household contact with chickenpox

Adult Exposure to Chickenpox Cuts Shingles Risk

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A modest but long-lasting protective effect was observed, but full protection not achieved
A two-dose course of recombinant zoster vaccine is associated with a reduction in the incidence of herpes zoster among adults who have undergone autologous hematopoietic stem cell transplantation

Two-Dose Course of Vaccine After HSCT Cuts Incidence of Zoster

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Incidence of herpes zoster decreased during median 21-month follow-up after autologous HSCT
From 2003 to 2014

2003 to 2014 Saw Incidence of Herpes Zoster Drop in Children

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Vaccinated children had 78 percent lower rate of HZ incidence than unvaccinated children
From 2004 to 2012

Herpes Zoster Ophthalmicus Cases Increased in 2004 to 2012

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Highest rates of HZO seen in older adults, women, and in whites versus other racial groups
Vaccination with recombinant zoster vaccine seems cost-effective under a wide range of conditions

Recombinant Zoster Vaccine Cost-Effective in Simulation

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Incremental cost-effectiveness ratio varied from $10,000 to $47,000 per QALY for RZV versus no vaccine
During the first eight months of recombinant zoster vaccine (RZV) use

CDC Examines Safety of Recombinant Zoster Vaccine

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Total of 4,381 reports of adverse events during first eight months of use; 3 percent were serious
The risk for herpes zoster is elevated during the two years preceding diagnosis and during treatment of hematological cancer

Risk for Zoster Up Before Dx, During Tx of Hematologic Cancer

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For solid organ cancers, the risk is greater among those receiving chemotherapy