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Tag: Herpes Simplex (Genital)

Three injections of a therapeutic vaccine may control herpes simplex virus 2 as effectively as daily pills for at least a year

ISDA: Vaccine Might Help Prevent HSV-2 Transmission

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Three-dose regimen seems as effective as daily pills, but more research needed
The U.S. Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus infection in adolescents and adults who are asymptomatic

USPSTF Recommends Against Screening for Genital Herpes

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Grade D recommendation against routine screening for asymptomatic adolescents and adults
There is a need for development of new anti-herpetic compounds with different mechanisms of action for herpes simplex viral keratitis

Treatment Options Reviewed for Herpes Simplex Viral Keratitis

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Options include acyclovir, valacyclovir, topical ganciclovir; need for development of new compounds
For older women

Herpes Simplex Virus Linked to Frailty, Mortality

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Only HSV-2 independently predicts five-year mortality risk in older women aged 70 to 79 years
In a letter to the editor published online March 24 in Clinical & Experimental Ophthalmology

Reactivation of HSV Described in Patient After Cataract Surgery

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Herpes simplex uveitis ID'd as cause of persistently elevated intraocular pressure after cataract sx
Activation of c-Jun N-terminal kinase is essential for herpes simplex virus gene expression during virus reactivation from latent neuronal infection

c-Jun N-terminal Kinase Essential for HSV Reactivation

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JNK signaling results in histone methyl-phospho switch on HSV lytic promoters
Pericoital application of tenofovir gel may substantially cut women's risk of contracting herpes simplex virus type 2

Tenofovir Gel Could Help Prevent Genital Herpes Simplex

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Pericoital application of tenofovir gel linked to reduced risk of HSV-2 infection
Unique presentation of herpes simplex virus infection in pregnancy can be misdiagnosed as premature rupture of membranes

Herpes Simplex Virus Can Mimic Premature Rupture of Membranes

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Case vignette describes woman with leakage of clear fluid, despite normal amniotic fluid volume
A genetically engineered form of the herpes virus is showing promise in slowing the progression of melanoma

HSV-Derived Immunotherapy Promising in Advanced Melanoma

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Study shows it helped a minority of patients, and experts say this approach has promise
The prodrug valacyclovir reduces viral load in HIV-1 infected herpes simplex virus-2-seronegative patients

Valacyclovir Cuts Viral Load in HIV-1+/HSV-2 Seronegative

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Prodrug valacyclovir active in HIV-1 infected patients who are HSV-2 seronegative