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Tag: Herpes Simplex (Genital)

Global Incidence, Prevalence High for Genital Herpes Simplex Virus Infections

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Number of people with at least one episode of HSV-attributable genital ulcer disease was 187.9 and 16.7 million for HSV-2, HSV-1 in 2020

Herpes Infections Recently Cost $35 Billion Globally

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Authors urge acceleration of herpes simplex virus vaccination efforts

USPSTF Reaffirms Recommendation Against Genital Herpes Screening

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Based on the evidence, the USPSTF continues to recommend against screening of asymptomatic adults and adolescents

Viral Shedding Common After First-Episode Genital HSV-1 Infection

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Genital HSV-1 shedding often asymptomatic; genital lesions, oral lesions, and oral viral shedding less common

USPSTF Continues to Recommend Against Genital Herpes Screening

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No new evidence identified to support changes to the 2016 recommendation against routine serologic screening for genital herpes

Subjects with Alzheimer's disease have increased levels of two strains of human herpesvirus

Increased Levels of Human Herpesvirus ID’d in Alzheimer’s

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Disruption of molecular, genetic, clinical networks by human herpesvirus in brains of subjects with AD
The prevalence of herpes simplex virus type 1 (HSV-1) and HSV-2 is 47.8 and 11.9 percent

HSV-1 Prevalence 47.8 Percent in 14- to 49-Year-Olds

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Prevalence of herpes simplex virus type 2 is 11.9 percent; both declined from 1999-2000 to 2015-2016
A new vaccine for herpes simplex virus type 2 could be nearing human clinical trials

Early Study Results Promising for Genital Herpes Vaccine

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Two-pronged approach tested on lab monkeys, guinea pigs
The novel herpes simplex virus (HSV) helicase-primase inhibitor pritelivir is more effective than valacyclovir for reducing genital HSV-2 shedding

Pritelivir Beats Valacyclovir for Genital HSV-2 Shedding

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Phase 2 trial shows decline in relative risk of herpes simplex virus shedding over 28 days
The U.S. Preventive Services Task Force recommends against routine serologic screening for genital herpes simplex virus infection in asymptomatic adolescents and adults

USPSTF Recommends Against Routine HSV Screening

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High proportion of false-positive results and associated psychological harms with screening