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Tag: Heartburn / GERD / Indigestion

Symptomatic gastroesophageal reflux disease is associated with chronic temporomandibular disorder

GERD Associated With Chronic Temporomandibular Disorder

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Somatization, anxiety, and undermined sleep moderately mediated correlation between GERD, TMD
Patients receiving gastric acid inhibitors have an increase in prescriptions of anti-allergic drugs

Risk for Allergy Development Increased After Gastric Acid Inhibitor Use

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Rates ratios increased with increasing age and were more prominent in women
Reflux symptoms return in about half of patients who undergo gastric bypass

Weight Loss Surgery May Not Relieve Acid Reflux

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Symptoms return in half of patients undergoing long-term follow-up after gastric bypass
Conservative measures to control reflux have limited effect on signs of gastroesophageal reflux in preterm infants

Pharmacologic Tx Should Be Used Sparingly for Reflux in Preemies

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Poor evidence of efficacy and evidence of harm with pharmacologic agents for gastroesophageal reflux
For patients with minor psychiatric disorders

DDW: Psych Disorders Make GERD Hard to Dx by Symptoms Alone

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Symptoms are unreliable for establishing presence of reflux in patients with minor psychiatric disorders
Diaphragmatic breathing can reduce belching and proton pump inhibitor-refractory gastroesophageal reflux

Diaphragmatic Breathing Tied to Less Belching in GERD

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The therapy is associated with reduced symptoms in patients with PPI-refractory gastroesophageal reflux
Gastroesophageal reflux disease is associated with a higher risk of cancer in the upper aerodigestive tract among the elderly population in the United States

GERD Linked to Upper Aerodigestive Tract Cancers

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In elderly, tied to higher odds of malignancy in larynx, hypopharynx, oropharynx, nasopharynx
Children with CYP2C19*17 alleles without corresponding loss-of-function alleles have longer times with pH <4 in response to proton pump inhibitor medication

CYPC19*17 Allele May Influence Response to PPI Treatment

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Kids with CYPC19&#42;17 alleles without corresponding loss-of-function alleles have longer times with pH &#60;4
Laparoscopic antireflux surgery is associated with a relatively high rate of recurrent gastroesophageal reflux disease

Antireflux Surgery Has High Rate of Recurrent Disease

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Nearly 18 percent have recurrence requiring long-term medication, secondary surgery
For infants with gastroesophageal reflux disease

Variation in Management for Infants With GERD

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Variation in overall utilization of anti-reflux surgery, and in surgical and diagnostic approach