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Tag: Heart / Stroke-Related: High Cholesterol

Less than an hour a week of resistance exercise is associated with decreased risks for cardiovascular disease-related events and all-cause mortality

Less Than One Hour of Resistance Training Weekly Tied to Lower CVD Risk

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No further risk reduction for CVD morbidity, all-cause mortality seen for ≥60 minutes/week
A healthy lifestyle for lowering cholesterol should be emphasized for reducing cardiovascular risk across the life course

AHA: Guidelines Stress Healthy Lifestyle for Lowering Cholesterol

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LDL-C should be reduced with high-intensity or maximally tolerated statin therapy
Intensive blood pressure control and fenofibrate use in patients with type 2 diabetes who are at high risk for cardiovascular disease may increase the risk for adverse kidney events

ASN: Aggressive Control of BP, Lipids in T2DM May Up Kidney Risk

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Strict BP control, fenofibrate use may increase long-term risk for adverse kidney events in T2DM patients
Genetic testing should become the standard of care for patients with definite or probable familial hypercholesterolemia

Genetic Testing Recommended for Familial Hypercholesterolemia

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Expert panel recommends genetic testing as standard of care for definite or probable cases
Low-density lipoprotein cholesterol and non-high density lipoprotein cholesterol ≥160 mg/dL are independently associated with increased relative risk of cardiovascular disease mortality in a low-risk cohort

High LDL in Young, Healthy Adults Leaves Them Vulnerable to CVD

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Findings may have implications for future cholesterol treatment paradigms
Elevated high-density lipoprotein cholesterol may not always be cardioprotective in postmenopausal women

‘Good’ Cholesterol May Not Be So in Postmenopausal Women

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High total HDL cholesterol in postmenopausal women may mask heart disease risk
There has been a substantial increase in the percentage of patients with high cholesterol over age 60 years taking lipid-lowering medications from 2005 to 2016

CDC: More People With High Cholesterol Taking Medications

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Findings only among men and women over 60 years, not younger patients with high cholesterol
The risk of having no or only one child is elevated for women with an unfavorable prepregnancy lipid profile

Unfavorable Prepregnancy Lipid Levels Linked to Low Parity

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Higher prepregnancy TG and TG:HDL-c ratio linked to increased risk of one lifetime pregnancy
There is a higher risk for early age-related macular degeneration in individuals with high plasma high-density lipoprotein cholesterol levels

Early Age-Related Macular Degeneration Linked to High HDL

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Incidence of early AMD 79.9 per 1,000 person-years in France
Only about 50 percent of adults with familial hypercholesterolemia are on statin therapy

Only Half of Adults With Familial Hypercholesterolemia on Statins

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And, only 30.3 percent of patients with definite or probable FH on statins take high-intensity statin