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Home Tags Heart / Stroke-Related: High Cholesterol

Tag: Heart / Stroke-Related: High Cholesterol

U.S. health experts voted on Tuesday to recommend approval of the first of two drugs in a new class of cholesterol medications that reduce low-density lipoprotein cholesterol in patients who don't fare well on statins. The related research was published online April 28 in the Annals of Internal Medicine.

FDA Panel Recommends Approval for PCSK9 Inhibitor

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Could be used by patients who don't respond to statins
Older patients taking statins or fibrates saw their risk of stroke over almost a decade decline by about one-third

Statins, Fibrates Linked to 30% Lower Stroke Risk in Elderly

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But no association between statins and lower risk of coronary heart disease in this group
Americans' levels of triglycerides have dropped significantly in the past decade

CDC: Triglyceride Levels Falling for Americans

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But many people still at risk
Statin use does not lower the risk of psoriasis

Statins Don’t Reduce Psoriasis Risk

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Findings among patients with high, long-term adherence to statins
A new class of cholesterol medication could sharply cut low-density lipoprotein cholesterol in patients who don't fare well on statins

PCSK9 Inhibitors Cut LDL Cholesterol, CVD Risk

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If approved, medications could be used by patients who don't respond to statins
Hydroxychloroquine appears to be associated with lower risk of hyperlipidemia in patients with early rheumatoid arthritis

Hydroxychloroquine May Reduce Hyperlipidemia Risk in Early RA

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Reduced risk of hyperlipidemia with hydroxychloroquine versus other DMARDs
Visit-to-visit variability in low-density lipoprotein cholesterol can independently predict cardiovascular events in individuals with coronary artery disease

Visit-to-Visit LDL-C Variability Predicts Cardiac Event Risk

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Variability predicts increased risk in patients with coronary artery disease, independent of LDL-C levels
Health coaching by medical assistants can help improve hemoglobin A1c and low-density lipoprotein cholesterol control

In-Clinic Health Coaching Improves Cardiometabolic Health

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Participants receiving health coaching by medical assistants have improved hemoglobin A1c, LDL
Evolocumab and alirocumab

ACC: PCSK9 Inhibitors Reduce LDL Cholesterol in Long Term

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Two studies show reductions in LDL cholesterol with evolocumab and alirocumab
People at age 55 who've lived with 11 to 20 years of high cholesterol show double the risk of coronary heart disease compared to people who age with only one to 10 years of high cholesterol

Duration of Hyperlipidemia in 30s/40s Impacts CHD Risk

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Researchers compare extended exposure to high cholesterol to "pack years" in smoking