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Risk of heart failure appears high within a few years of a first myocardial infarction

Heart Failure Risk Up Significantly After First Myocardial Infarction

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One in four MI survivors develop heart failure within four years
An updated clinical guideline adds two new types of drugs to the list of treatment options for heart failure. The updated guideline was published online May 20 in the Journal of the American College of Cardiology

Two New Drugs Added to Heart Failure Clinical Practice Guideline

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Heart groups issue updated guideline for the treatment of heart failure
Adherence to heart failure process of care measures has improved significantly over the last 10 years for patients with acute decompensated heart failure with reduced ejection fraction and end-stage renal disease

Recent Improvement in Heart Failure Process of Care Measures

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Findings for patients with acute decompensated heart failure with reduced ejection fraction, ESRD
Use of saxagliptin or sitagliptin is not associated with increased risk of hospitalized heart failure compared with other antihyperglycemic agents

Saxagliptin, Sitagliptin Don’t Up Hospitalized Heart Failure

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No increased risk for new users of saxagliptin, sitagliptin versus other antihyperglycemic agents
For patients with post-myocardial infarction heart failure

Mineralocorticoid Receptor Antagonists No Benefit Post MI

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MRA in addition to standard therapy does not improve outcome in setting of post-MI heart failure
For patients with heart failure with reduced ejection fraction

Sacubitril-Valsartan May Be Cost-Effective Option in HFrEF

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More costly than enalapril but more effective over a lifetime in heart failure with reduced ejection fraction
For patients with worsening heart failure

Diuretic Dose Not Linked to Outcome in Heart Failure

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In multivariate analysis, no correlation seen for patients with worsening heart failure
Hispanics/Latinos frequently have cardiac dysfunction

Subclinical Cardiac Dysfunction Frequent in Hispanics/Latinos

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High rate of left ventricular diastolic dysfunction; most cardiac dysfunction is subclinical, unrecognized
Regular doses of vitamin D3 may improve cardiac function in heart failure patients

ACC: Vitamin D Found to Improve Cardiac Function in Heart Failure

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Further studies necessary to determine whether this translates to improvements in outcomes
Ixmyelocel-T

ACC: Ixmyelocel-T Beneficial for Heart Failure With Reduced EF

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Significant reduction in primary efficacy end point with ixmyelocel-T therapy