Tag: Genetics

Patients with sustained minimal residual disease negativity had longer time to next treatment, regardless of baseline risk characteristics

Model, which considers 10 genes from UroAmp uCGP test, had high sensitivity and specificity in two validation cohorts

Persistence of FLT3-ITD and/or NPM1 in blood associated with relapse and worse survival among acute myeloid leukemia patients

Higher genetically predicted plasma caffeine concentrations linked to lower risk for type 2 diabetes, with 43 percent of effect mediated by BMI

Risk reduction surgeries before age 50 years substantially cut later cancer risk for those with genetic risk

Multiancestry polygenic risk score can stratify prostate cancer risk and differentiate risk for aggressive disease

Study shows that polygenic score does not modify the 13 percent reduction in ovarian cancer risk seen with aspirin

Findings seen for major depression, bipolar disorder, schizophrenia

Increased risk for Alzheimer disease and younger age of onset seen with APOE ε3 R145C missense variation

Nonshared environmental factors explain 21 percent of the condition in twin study