Tag: Genetics

Genetically adjusted prostate-specific antigen more predictive of aggressive prostate cancer than unadjusted PSA

Rates of testing lower among Asian, Black, and Hispanic patients versus White patients

Genetically determined high-density lipoprotein cholesterol and systolic blood pressure linked to increased odds of Alzheimer disease

Findings based on a subset of 10 genes with greatest predictive power

Low-density lipoprotein cholesterol goals achieved by a minority of adults and children despite multiple lipid-lowering treatments

Genomic screening for Lynch syndrome, hereditary breast and ovarian cancer syndrome, and familial hypercholesterolemia likely cost-effective for adults younger than 40 years

Positive association was robust when MR Egger, weighted median, weighted mode were exploited

Diagnosis made in about 41 percent of probands with severe disorder; 76 percent had pathogenic de novo variant

High satisfaction reported for genetic testing model including education, follow-up with genetic counselor

Additive risk seen, with more than twofold higher risk for combination of poor sleep and high genetic susceptibility