Tag: Genetics

Low-density lipoprotein cholesterol goals achieved by a minority of adults and children despite multiple lipid-lowering treatments

Genomic screening for Lynch syndrome, hereditary breast and ovarian cancer syndrome, and familial hypercholesterolemia likely cost-effective for adults younger than 40 years

Positive association was robust when MR Egger, weighted median, weighted mode were exploited

Diagnosis made in about 41 percent of probands with severe disorder; 76 percent had pathogenic de novo variant

High satisfaction reported for genetic testing model including education, follow-up with genetic counselor

Additive risk seen, with more than twofold higher risk for combination of poor sleep and high genetic susceptibility

Interaction identified between H. pylori infection and pathogenic variants in homologous-recombination genes

Circadian pattern of attacks identified, and circadian associations seen at systems and cellular levels

Nineteen independent SNPs identified that were genome-wide significant for general addiction risk factor

Seventeen variants identified as potentially oncogenic in 17.7 percent of South African male patients