Tag: Genetics
Call for Gene Tests in Cancer to Include Normal Tissue
Current practice of only focusing on tumor samples might adversely affect care
Lansoprazole Worsens Asthma Control in Poor Metabolizers
After six months of treatment, worse control in children with poor CYP2C19 metabolizer phenotype
Placebo Response May Depend on Individual DNA
But more questions than answers exist at this point
Higher Risk of Heart Disease Seen With Shorter Stature
Increased risk possibly linked to the genetics that also determine height
Breast, Ovarian CA Risk Varies With BRCA Mutation Location
Nonsense-mediated decay mutations linked to differential breast or ovarian cancer risk
Breast CA Patients Want, but May Not Get, Genetic Risk Discussion
Almost half don't have conversation with doctor about potential for future problems
PTEN Regulation of Insulin Resistance Is Sex Specific
Women have downregulation of PTEN gene expression, upregulation of PTEN protein phosphorylation
Genetic Variation Impacts Aspirin/NSAID Link to CRC Risk
Use of aspirin, NSAIDs lowers risk of CRC in association with genetic variation at two SNPs
Frequency of Germline TP53 Mutations ID’d in Early-Onset CRC
Germline mutations detected at a frequency of 1.3 percent in patients with early-onset colorectal cancer
Poll: Majority of Americans Interested in Genetic Testing
But researchers wonder if everyone is adept at accurately interpreting test results
