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U.S. children with a genetic polymorphism affecting FUT2 secretor status appear to be protected from severe rotavirus gastroenteritis

Rotavirus Gastroenteritis Almost Absent in FUT2 Nonsecretors

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U.S. children with genetic polymorphism affecting secretor status seem to be protected from rotavirus
MiRNA-506 is involved in gastric cancer

miRNA-506 Affects Metastasis, Angiogenesis in Gastric Cancer

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Overexpression inhibits the epithelial-to-mesenchymal transition of gastric cancer cells
An ethical framework has been developed to guide the professionally responsible disclosure of results of genomic sequencing in pediatric practice. The guidance is presented in a special article published online Sept. 14 in Pediatrics.

Ethical Framework Developed for Genomic Testing Results

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Discussion of professionally responsible disclosure of results to parents and pediatric patients
Risk of rosacea appears to be half environmental and half genetic

Genetics, Environment Equally Contribute to Rosacea

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For those with family history, limiting sun exposure can help curb condition
A pair of genetic tests

Genetic Tests Could Improve Management of Autism

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Researchers anticipate genetic testing of children with autism will continue to increase
For some pediatric cancer patients with relapsed or refractory cancer

Genomic Sequencing Benefits Some Childhood Cancer Patients

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Benefits seen for some children and young adults with relapsed or refractory cancer
A comprehensive approach can improve molecular analysis of PMS2 for patients with Lynch syndrome

Comprehensive Strategy IDs Mutation in Homologous Genes

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Approach can accurately detect mutations in genes with multiple copies of highly homologous sequences
Young black women have a higher rate of BRCA1 or BRCA2 gene mutations than previously believed

Higher Frequency of BRCA Mutations Seen in Black Women

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In study of those under 50 with invasive form of disease, 12 percent had BRCA1, BRCA2 mutations
Excision repair cross-complementing group 1 genotype for the single nucleotide polymorphism cytosine-to-thymine substitution at codon 118 interacts with post-radiotherapy plasma Epstein-Barr virus DNA to identify favorable prognosis for a subgroup of patients with nasopharyngeal carcinoma

ERCC1 SNP Can Identify Good Prognosis in Nasopharyngeal CA

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ERCC1 C118T genotype may identify good prognosis in subgroup of pEBV-negative patients
For adult patients with de novo acute myeloid leukemia

Genomic Approach Could Aid Risk Stratification in Adults With AML

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Persistent leukemia-linked mutations in remission samples tied to increased relapse, worse survival