Tag: Genetics
Comprehensive Strategy IDs Mutation in Homologous Genes
Approach can accurately detect mutations in genes with multiple copies of highly homologous sequences
Higher Frequency of BRCA Mutations Seen in Black Women
In study of those under 50 with invasive form of disease, 12 percent had BRCA1, BRCA2 mutations
ERCC1 SNP Can Identify Good Prognosis in Nasopharyngeal CA
ERCC1 C118T genotype may identify good prognosis in subgroup of pEBV-negative patients
Genomic Approach Could Aid Risk Stratification in Adults With AML
Persistent leukemia-linked mutations in remission samples tied to increased relapse, worse survival
BRAF V600 Is Targetable in Some Nonmelanoma Cancers
Vemurafenib active in NSCLC, Erdheim-Chester disease, Langerhans'-cell histiocytosis
Role of SNP Variant in FTO Explored in Obesity
Study identifies mechanistic basis for the strongest genetic association with obesity
Most Lice Populations Show Resistance to Pyrethroids
104 of 109 samples from 30 states were 100 percent resistant in three point mutations
RAD51 Mutations Confer Moderate Risk of Ovarian Cancer
RAD51C and RAD51D deleterious mutations linked to increased risk of epithelial ovarian cancer
Genetic Variant Ups Risk of Graft-Versus-Host Disease in HSCT
Rejection seen with high-expression allele recipient, low-expression allele donor in HLA-DPB1 mismatches
Multigene Test IDs More at Risk for Hereditary Breast/Ovarian CA
Testing for mutations other than BRCA1/2 in HBOC may change clinical management for women, families
