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Tag: Genetics

Genetic Factors Influence Subsequent Cancer Risk in Childhood Cancer Survivors

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Examination of joint links between polygenic risk scores and radiotherapy show more than additive increases in risk for some cancers

Blacks Less Likely to Undergo Evaluation for Genetic Testing

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Among patients with neurologic conditions, Blacks are less likely than Whites to undergo evaluation for genetic testing

Race Can Affect Breast Cancer Test for Predicting Chemo Benefit

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21-gene recurrence score may underestimate benefit of chemotherapy for young non-Hispanic Black women with ER-positive, axillary node-negative breast cancer

GERD Can Induce Occurrence of Rheumatoid Arthritis, but Not Vice Versa

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Bidirectional Mendelian randomization analysis showed 69 percent increased risk for RA occurrence for GERD patients

Inherited Genetic Loci Identified for Thinner Retinal Layers Using Optical CT

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Thinner retinal layers phenotypically associated with ocular, neuropsychiatric, cardiometabolic, pulmonary conditions

Ten Variants Suggest Link to Surgical, Nonsurgical Rhizarthrosis

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Seven variants suggest association with surgical rhizarthrosis; all 10 variants differed significantly between treatment groups

Risk for Cancer Increased for Relatives of Patients With Leukemia

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Study finds increased risk for cancer overall and for specific cancers for first- and second-degree relatives

Anorexia Associated With Being an Early Riser

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Findings seen in both a genetic association study and among biobank participants

Twin’s Dementia Tied to Shorter Life Expectancy in Unaffected Twin

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Findings seen for both identical and fraternal twins and for the affected twin compared with the general population

SABCS: 22 Percent of Young BRCA Carriers Conceive After Breast Cancer

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No significant difference seen in disease-free survival for those with, without pregnancy; overall survival up for those with pregnancy