Tag: Genetics
Ten Variants Suggest Link to Surgical, Nonsurgical Rhizarthrosis
Seven variants suggest association with surgical rhizarthrosis; all 10 variants differed significantly between treatment groups
Risk for Cancer Increased for Relatives of Patients With Leukemia
Study finds increased risk for cancer overall and for specific cancers for first- and second-degree relatives
Anorexia Associated With Being an Early Riser
Findings seen in both a genetic association study and among biobank participants
Twin’s Dementia Tied to Shorter Life Expectancy in Unaffected Twin
Findings seen for both identical and fraternal twins and for the affected twin compared with the general population
SABCS: 22 Percent of Young BRCA Carriers Conceive After Breast Cancer
No significant difference seen in disease-free survival for those with, without pregnancy; overall survival up for those with pregnancy
Clot Risk High With Oral Contraceptives for Those at Genetic Risk
Risk highest in the first two years, regardless of genetic risk, and lower for continued use
Polygenic Predisposition to Short Sleep Linked to Depression
No association seen for polygenic score for depression with overall sleep duration, short sleep, or long sleep
Concurrent RNA and DNA Sequencing Improves Variant Detection
Overall, 17.1 percent of 545 pathogenic/likely pathogenic splicing variants were dependent on RNA evidence for classification
Genetic Predisposition to Insomnia Linked to Insomnia-Like Problems
Children with polygenic risk score for insomnia have more insomnia-related sleep problems between ages 1.5 and 15 years
Risk-Adapted Starting Age of CRC Screening Varies by Sex, Genetics
Risk-adapted starting age of screening varies by 24 years for men in highest polygenic risk score decile versus women in lowest
