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Genetic variants have been identified in psoriasis patients that correlate with anti-tumor necrosis factor-α treatment response

Genetic Variants ID Treatment Response in Psoriasis

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Ten SNPs presented that correlate with treatment responses to anti-TNF-α agents
A man's risk of aggressive and fatal prostate cancer may be heavily influenced by gene mutations previously linked to breast and ovarian cancer in women

AUA: BRCA Mutations May Play Role in Prostate Cancer

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Multiple studies suggest they might
Data from a large cohort have replicated the association between the genetic risk score of 11 favorable adiposity variants with lower risk of cardiometabolic disease

Adiposity Genetic Risk Score Tied to Cardiometabolic Health

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Genetic risk score from 11 variants linked to lower risk of type 2 diabetes, hypertension, heart disease
A mutation has been identified in MAGED2 that causes transient antenatal Bartter's syndrome

MAGED2 Mutation Causes Antenatal Bartter’s Syndrome

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Symptoms disappeared spontaneously during follow-up in infants who survived
The drug eteplirsen should not be approved for treatment of Duchenne muscular dystrophy

FDA Panel Votes Against Approval of Eteplirsen for DMD

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Clinical data did not meet the agency's requirements for well controlled studies necessary for approval
Histamine may contribute to exercise recovery in skeletal muscle

Do Antihistamines Blunt Exercise Recovery?

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Histamine blockade changes expression of genes that respond to exercise
The BRCA1 gene mutation may also be tied to potential fertility issues

BRCA1 Mutation May Reduce Women’s Fertility

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The BRCA1 mutation may speed the aging of a woman's ovaries
Many breast cancer patients receive chemotherapy they don't need

AACR: Many Breast Cancer Patients May Not Need Chemo

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Genetic test can help doctors determine who can safely avoid treatment after surgery
Telomere length is associated with an increased risk of myocardial infarction

Telomere Length Tied to Higher Myocardial Infarction Risk

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Large multiethnic study shows linear relationship when telomere length is divided into tertiles
Genetics could play a role in the development of melanoma even for skin without extensive sun exposure

MC1R Variants May Up Melanoma Risk, Even Without Sun Exposure

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Variant of gene linked to skin pigmentation tied to higher risk