Tag: Genetics
‘Ice Bucket Challenge’ Led to Significant ALS Gene Discovery
Money raised during the campaign helped scientists ID gene linked to amyotrophic lateral sclerosis
Effects of APOE Gene May Be Apparent in Childhood
Findings may lead to earlier interventions, preventive measures for future brain injuries, dementia
Risk Score Could Help ID Alzheimer’s Risk in Young Adults
Score also associated with worse memory, clinical progression in older adults
Genetic Risk Score Impact on BMI Varies Across Birth Cohorts
Larger magnitude of association between genetic risk score for BMI and BMI in later birth cohorts
Elevated Risk of Death for Osteogenesis Imperfecta
Higher risk of death from respiratory diseases, gastrointestinal diseases, and trauma
Two-Stage Screening Could Be Cost-Effective for Trisomy
Cost-benefit analysis of hypothetical
model based on implementation of cell-free fetal DNA
CVD Risks Way Up in Familial Hypercholesterolemia
Clinician-patient discussions on guideline-supported therapies can be informed by data
BRCA1 Mutations May Raise Risk of Serous/Serous-Like Uterine CA
Although overall risk for uterine cancer after risk-reducing salpingo-oophorectomy not increased
Clopidogrel Plus Aspirin Good for Noncarriers of CYP2C19 Variants
Reduction in risk of new stroke for clopidogrel plus aspirin in those not carrying loss-of-function alleles
Coenzyme Q10 Levels Linked to Multiple System Atrophy
Decreased levels of plasma CoQ10 in patients with MSA, regardless of genotype
