Tag: Genetics
TP53, MDM2 Alterations Linked to Cisplatin Resistance in GCT
TP53, MDM2 alterations predict adverse prognosis in patients with germ cell tumors
FTO Gene Does Not Inhibit Weight Loss Success
Lifestyle, environment likely play bigger roles when losing weight, researchers say
Experimental Drug Shows Promise in Melanoma
Pevonedistat was effective for inhibiting proliferation of melanoma cell lines in vitro
FGF21, Dietary Intake Interaction Impacts Adiposity
FGF21 genotype interacts with dietary carbohydrate/fat intake to affect adiposity, body fat
Novel Findings Support Original Categorization of HER2
ASCO-CAP guidelines support categorization of HER2 by FISH status used in BCIRG clinical trials
TBC1D4 Mutation Common in North American Inuit
TBC1D4 carriers with prediabetes, type 2 diabetes have increased risk of remaining undiagnosed
Biomarker Score May Help Predict Response to Cancer Treatment
Researchers say finding might help identify patients most likely to be helped by chemotherapy, radiation
Bronchiolitis Plus Gene Variant Raises Asthma Risk in Children
Higher risk seen in those with PAI-1 gene variant and serious respiratory infection at a young age
Genetics May Help Identify Infection in Febrile Infants
Goal is to distinguish between bacterial, viral illness, researchers say
Success, Safety Up for ART With Elective Single Embryo Transfer
Risks are much higher in multifetal gestations, but are also seen for singletons achieved with ART