Tag: Genetics
ASCO: Gene-Targeted Drug Shows Efficacy for Child, Adult Cancers
Larotrectinib targets tropomyosin receptor kinase fusion proteins
MTHFR A1298C Polymorphism Not Linked to MTX Outcomes in RA
No significant link for MTHFR gene A1298C polymorphism with methotrexate efficacy, toxicity
Progress Made on Genetic Test for Anal Cancer
But research is still in early stages
Combined Urine Test for T2:ERG, PCA3 Ups Prostate CA Detection
Combined urinary testing can avoid unnecessary prostate biopsy, while preserving high sensitivity
Adding Selumetinib to Docetaxel Doesn’t Up PFS in NSCLC
No improvement in progression-free survival for previously treated advanced KRAS-mutant NSCLC
BDNF Gene Mutation May Speed Up Memory Loss in Alzheimer’s
If β-amyloid plaques are present in the brain, process is even faster, researchers say
Exercise Reduces Weight Gain Effects in Those With FTO Gene
No evidence for interaction with physical activity for loci other than established FTO locus
Enzyme Replacement Drug OK’d for Form of Batten Disease
Brineura will be used to treat children with late infantile neuronal ceroid lipofuscinosis type 2 Batten
Gene Expression Profile Improves ID of High-Risk Melanoma
Findings based on use of 31-gene profile along with an online survival prediction tool
Genetic Variant Tied to MS and Systemic Lupus Identified
However, BAFF variant was likely selected over time as an adaptive response to malaria
