Tag: Genetics
GWAS Identifies 108 Independent Risk Loci for Kidney Cancer
Validated polygenic risk score generated, with area under the curve of 0.65 among European ancestry individuals
Recombinant ADAMTS13 Effective, Safe in Congenital Thrombotic Thrombocytopenic Purpura
Treatment had few adverse events and increased ADAMTS13 activity versus standard therapy
Healthy Lifestyle Can Overcome Genetic Predisposition to Premature Death
Optimal healthy lifestyles include never smoking, regular physical activity, adequate sleep duration, and a healthy diet
Patient Gets First-Ever Pig Kidney Transplant Plus Heart Pump
New Prostate Cancer Urine Test Has High Diagnostic Accuracy
Higher AUROC seen for 18-gene MPS2 model compared with current guideline-endorsed biomarkers
Heritability for Autism Spectrum Disorder Varies for Males and Females
Difference in heritability estimated at 11.3 percent, with higher heritability for males than females
Study IDs Risk Factors for Extraintestinal Manifestations of IBD
Being female, smoking, previous surgeries for IBD, and genetics all tied to higher risk
Patient Enrollment in Cancer Treatment Trials About 7 Percent
One in five patients with cancer participate in any cancer-related trial, including biorepository, registry, genetic, and quality-of-life studies
Risk for Second Primary Breast Cancer Low in Certain Young Breast Cancer Patients
Young breast cancer survivors without pathogenic variant have low risk for developing second primary breast cancer
More Physical Activity Needed to Cut Risk for Obesity Among Those With Genetic Risk
As polygenic risk score increases for BMI, number of daily steps associated with lower risk for obesity increases
