Tag: Genetics

Maternal, paternal obesity at age 17 years tied to fivefold higher odds of offspring obesity at age 17 years

Odds ratio of 7.08 for atrial fibrillation for rare pLOF variants combined with high polygenic risk score

AA genotype linked to reduced severity, but not occurrence, of TD; no association seen for rs210133 with TD occurrence, severity

Lifetime cumulative risk for advanced gastric cancer 10.3 and 6.5 percent for male and female carriers, respectively

Onset of cognitive impairment delayed among those heterozygous for the apolipoprotein E3 Christchurch variant

Unique environmental effects, but not a shared environment between siblings, also influences risk

Crinecerfont results in greater decrease from baseline in mean daily glucocorticoid dose among patients with CAH

Almost all patients with nail involvement had polydactylous involvement with onychopapillomas

Carriers face similar and substantial risk for heart failure hospitalization, mainly with reduced ejection fraction

Clinically meaningful differences in BP and increased HTN risk seen in top versus bottom decile of polygenic risk scores