Tag: Genetics
Recommendations Presented on Genetic Testing in Psychiatry
Guidelines emphasize that common genetic variants are not sufficient to cause psychiatric disorders
ENDO: Sex Hormone Levels Tied to Telomere Length in Older Men
Estradiol independently linked to leucocyte telomere length in older men; SHBG inversely associated
Having Affected Relatives Linked to Increased Alzheimer Risk
Increased Alzheimer disease risk seen with having affected first-, second-, or third-degree relatives
Parity, Risk for Breast Cancer Studied for BRCA1/2 Carriers
Higher risk seen in uniparous BRCA1 carriers, parous BRCA2 carriers; breastfeeding cuts risk in BRCA1
Genetic Testing Recommended for All Patients With Breast Cancer
All with personal history of breast cancer should be offered testing; updated testing recommended
Endogenous Testosterone Linked to Cardiovascular Disease
Genetically predicted endogenous testosterone may have role in thromboembolism, heart failure, MI
Blood Test Offers Early Warning for Kidney Transplant Rejection
Monitoring for certain genes in peripheral blood samples might predict rejection before it occurs
Liquid Biopsy-Based Test IDs Biomarkers in Metastatic NSCLC
Test led to increase in number of patients with identified G7 biomarker, reduction in turnaround time
Genetic Variant Tied to Leukemia Risk in Hispanic Children
Novel susceptibility locus identified in the ERG gene for acute lymphoblastic leukemia
Oncotype DX Not Cost-Effective for Low-Risk Breast Cancer
Incremental cost-effectiveness ratio varies across clinical risk groups, sensitive to patient age
