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An integrated approach using data from the Chronic Obstructive Pulmonary Disease Genetic Epidemiologic study could identify individuals with possible or probable COPD as well as definite COPD

Expansion of Diagnostic Criteria Proposed for COPD

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Expanded diagnostic criteria used to classify individuals with possible, probable, definite COPD
For three commercial panels for prostate cancer prognosis

Racial Differences Found in Gene Panels for Prostate Cancer Prognosis

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Gene expression differs for European-American men, African-American men for three commercial panels
For patients with obesity

Bariatric Surgery in Obese Patients May Lower Cancer Risk

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Among genetically predisposed, breast cancer rate higher in those who did not opt for bariatric surgery
Only half of oncologists who discuss genomic testing with patients report that they often discuss the likely costs of testing and related treatments

Many Oncologists Fail to Discuss Costs of Genomic Testing

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About a quarter of oncologists say they rarely, never bring up costs when they discuss genomic testing
The FIND FH model can successfully identify individuals with familial hypercholesterolemia from a scan of large

AI Model Helps ID Those at Risk for Familial Hypercholesterolemia

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Model may identify more who are at risk while substantially reducing the number of people screened
Initiation of statin therapy during childhood in patients with familial hypercholesterolemia slows the progression of carotid intima-media thickness and reduces the risk for cardiovascular disease over 20 years

Statins in Childhood Aid Familial Hypercholesteremia Outcomes

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Patients show slowed progression of carotid intima-media thickness, lower risk for cardiovascular disease
A triplet combination of therapies (encorafenib

Triplet Tx Ups Survival in BRAF V600E-Mutated Colorectal Cancer

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Overall survival longer for encorafenib, cetuximab, and binimetinib combo versus standard therapy
The first attempt to use the gene-editing tool CRISPR to cure HIV infection was unsuccessful but the approach does show promise.

Scientists Use Gene-Editing Tool CRISPR in Attempt to Cure HIV

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Attempt failed, but tool appears precise and safe and holds promise
Use of a response- and biology-based treatment algorithm for intermediate-risk neuroblastoma is associated with excellent survival and reduces treatment for some patients

Algorithm Based on Response, Biology Guides Neuroblastoma Tx

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Survival excellent with treatment algorithm for children with intermediate-risk neuroblastoma
The U.S. Preventive Services Task Force recommends that women who are at increased risk for BRCA1/2 mutations should undergo genetic counseling

USPSTF Recommends Genetic Counseling for High BRCA Risk

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But counseling not recommended for women without personal, family history, ancestry associated with BRCA mutations