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Maximal resection of a contrast-enhanced tumor is associated with improved overall survival in patients with isocitrate dehydrogenase gene 1 or 2 (IDH)-wild-type and IDH-mutant subtype glioblastomas

Maximal Resection of Glioblastomas May Up Survival

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Maximal resection of contrast-enhanced tumor linked to increased overall survival across all subgroups
The genetic determinants of testosterone levels differ between the sexes

Genetic Basis for Testosterone Levels Differs According to Sex

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Genetically higher testosterone level generally benefits men, harms women in metabolic diseases
Among those who have Helicobacter pylori infection and a family history of gastric cancer in first-degree relatives

H. pylori Eradication Cuts Gastric Cancer Risk in Those With Family History

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Gastric cancer risk reduced among those with H. pylori infection plus first-degree relatives with gastric cancer
Obesity does not necessarily induce or contribute to familial psoriasis

Familial Psoriasis May Not Be Tied to Obesity

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Patients with familial psoriasis were younger, had a lower BMI at diagnosis versus nonfamilial psoriasis
In a special communication article

Public Policy Recs Updated for Familial Hypercholesterolemia

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Goals include enhancing awareness of familial hypercholesterolemia as a global public health issue
Autism spectrum disorder is markedly heritable

Severity of Autism Symptoms May Vary in Monozygotic Twins

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Trait correlations for MZ twins differed according to the clinical range of severity for autistic symptoms
The Chinese scientist who claimed he had created the first genetically edited babies in the world was sentenced to three years in prison for his research

China Convicts Scientists Claiming First Genetically Edited Babies

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Scientists convicted of practicing medicine without license, violating Chinese regulations on research
A polygenic risk score

Polygenic Risk Score More Strongly Linked to Early-Onset CRC

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Strongest association seen for participants without a first-degree family history of colorectal cancer
For patients with previously untreated advanced non-small cell lung cancer with an EGFR mutation

First-Line Osimertinib May Up Survival in EGFR-Mutated NSCLC

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For previously untreated disease, overall survival longer with osimertinib versus comparator EGFR-TKIs
Systematic prostate-specific antigen screening is advised for men who are carriers of the BRCA2 mutation

Study Supports PSA Screening for Male BRCA2 Carriers

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Further follow-up needed to assess benefit of PSA screening in male BRCA1 mutation carriers