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Tag: Genetics

Deep-Learning Algorithm Helps Radiologists ID Cerebral Aneurysm

RSNA: Anxiety May Hasten Progression to Alzheimer Disease

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Rate of progression from MCI to AD increased with ApoE4, anxiety, lower hippocampal and entorhinal cortex volumes

Genetics Tied to Thromboembolism Risk With Inflammatory Bowel Disease

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Genetic signature tied to doubled risk for developing potentially fatal blood clots in one in seven IBD patients

Positive BRCA Test Results Down From 2008 to 2018

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Socioeconomic and regional disparities persist in the use of BRCA testing

Broader Genetic Testing Could ID More Heritable Cancers

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Universal genetic testing catches genetic mutations not detected in guideline-based testing

High SARS-CoV-2 Genomic Load Tied to Worse Outcomes

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Genomic load independent risk factor for composite outcome of death, intubation, ECMO

American and French scientists have won the 2020 Nobel Prize in chemistry for their work developing the revolutionary gene-editing tool CRISPR-Cas9.

U.S., French Researchers Awarded Nobel Prize in Chemistry

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Recipients are University of California at Berkeley biochemist Jennifer Doudna and Emmanuelle Charpentier of France
In a genome-wide association study

14 Novel Loci Identified for Abdominal Aortic Aneurysm

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Genetic increase of 10 mm Hg in diastolic blood pressure likely has causal link with AAA
Genetically predicted body mass index significantly increases the risk of rheumatoid arthritis

Genetically Predicted BMI Increases Rheumatoid Arthritis Risk

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Effect consistent across sensitivity analyses and comparable for men and women
Genotyping may provide some clinical benefit in prescribing antiplatelet therapies for patients undergoing percutaneous coronary intervention

CYP2C19 Genotyping May Aid Antiplatelet Prescribing

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Benefit only seen for composite outcome, not for major or minor bleeding incidents
Genetic editing of embryos should not be attempted yet because the science is not advanced enough to ensure safety

Science Not Yet Advanced Enough for Genetic Editing of Embryos: Expert Panel

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However, panel has not taken a position on whether genetic editing of embryos is ethical