Tag: Genetics
Causal Link Suggested for Smoking, Subarachnoid Hemorrhage
Genetic susceptibility to smoking, assessed using polygenic risk score, is associated with increased risk for SAH
Autistic Traits ID’d in Carriers of CNVs Linked to Autism
54 percent of carriers of certain copy number variants have elevated levels of autistic traits
Polygenic Risk Scores May Improve IBD Risk Prediction
For every population in BioMe biobank, combining risk scores from distinct ancestral populations improved risk prediction for IBD
Triple Treatment Combo Beneficial in BRAF-Mutant CRC
Irinotecan, cetuximab, and vemurafenib improve progression-free survival in BRAFV600E-mutated colorectal cancer
U.S. Army Researchers Analyze New Coronavirus Variant
Walter Reed team is checking genetic sequences of the mutated virus variant
HFE Hemochromatosis May Up Risk for Liver Cancer in Men
Risk for incident primary hepatic malignancy and death increased among men with HFE p.C282Y homozygosity
ASH: CRISPR-Cas9 Gene Editing Promising in TDT, SCD
Total hemoglobin, fetal Hb increased in seven patients with transfusion-dependent ß-thalassemia, three with sickle cell disease
Genetic Ancestry Tied to Lung Cancer Mutations in Latin Americans
Mutation frequencies of EGFR and KRAS were 30 and 10 percent, respectively, and 23 and 13 percent, respectively, for Mexican and Colombian patients
ASH: CRISPR-Cas9 Gene Editing Promising in TDT, SCD
Total hemoglobin, fetal Hb increased in five patients with transfusion-dependent ß-thalassemia, two with sickle cell disease
ASH: Black Race Linked to Poorer Survival in AML
Among AML patients treated on Alliance protocols, Blacks versus Whites had inferior disease-free, overall survival
