Tag: Genetics
Teen, Parent Response Explored for Cardiomyopathy Genetic Tests
Families with positive predictive test results had better functioning scores than those with negative predictive test results
WHO Calls for Global Registry of Human Genome Editing
Studies involving human genome editing should be made public, even though it would not necessarily stop unprincipled scientists
Oral Contraceptives Lower Ovarian Cancer Risk in BRCA Carriers
Findings seen in BRCA1 and BRCA2 mutation carriers; reduction greater with longer duration of use in BRCA1 carriers
Racial Differences Seen in Inherited Risk of Early-Onset Cancer
Higher familial risks for early-onset cancer seen in Latinos, Blacks for solid tumors and in Asian/Pacific Islanders for hematologic cancers
Genetic Risk Score May Predict Adolescent Idiopathic Scoliosis
Odds ratio for developing AIS was 3.36 for the highest decile for PRS versus the fifth decile, which was designated as the average-risk group
Genetic Predisposition + High Caffeine Intake Ups Risk of Increased Intraocular Pressure
High caffeine intake not associated with increased risk for higher IOP or glaucoma, overall; among those with genetic risk, caffeine consumption increases risk of glaucoma
New Gene Variants Identified That May Raise Risk for ALS
Mutations identified in TP73 in ALS patients; mutations caused abnormal differentiation, apoptosis in myoblast differentiation assay
ASCO: Sotorasib Targets KRAS p.G12C-Mutated NSCLC
Objective response seen in 37.1 percent of patients with previously treated KRAS p.G12C-mutated non-small cell lung cancer
CRC Risk Up in First-Degree Relatives of Patients With Polyps
Link between family history of polyps and CRC risk strengthened with increasing number of relatives and lower age at polyp diagnosis
Universal Multigene Panel Test in CRC IDs Heritable Mutations
Sequencing results from universal panel changed cancer treatment for roughly one in 10 colorectal cancer patients
