Tag: Genetics
Inflammation Linked to Inferior Outcomes in Leukemia
Inflammation-associated gene score identified in patients with acute myeloid leukemia, which is associated with poor survival outcomes
Sequencing IDs Genetic Diagnoses for Sensorineural Hearing Loss
Causal variants identified in 43 genes; almost all children had causative variant(s) in only one gene
Waist-to-Hip Ratio Genetic Risk Score Inversely Linked to Weight Loss
Findings seen in participants with severe and complicated obesity who completed a 24-week milk-based meal-replacement program
On-Site Genetic Testing for Prostate Cancer Increases Patient Compliance
Implementation of on-site guideline-based genetic testing for prostate cancer patients increased compliance from 33.3 to 98.7 percent
Genetic + Registry Data AI Model May Predict Mental Disorder Diagnosis
Deep learning, multidiagnostic model shows high accuracy before clinical examination
Lifestyle May Counter Genetic Risk for Thyroid Cancer
Highest risk for thyroid cancer seen among participants with both high genetic risk and unfavorable lifestyle
Oncogenic Variants Identified in ~10 Percent With Appendix Cancer
Mutations identified in MUTYH, in the MLH1 gene, and in other cancer predisposition genes
Education Interacts With Genetic Variants to Increase Myopia Risk
Genotype by education interaction identified for five genetic variants, with increased effect for university-level education
Stable Neurodevelopment Seen for Most Children With Familial High Risk for Schizophrenia
12.8 percent of children with familial high risk for schizophrenia, bipolar disorder transition to different neurocognitive subgroup
AI Algorithm May ID Dysfunctional Immune Profiles in Acute Infection
Machine learning framework used to deploy quantitative sepsis response signature score, which was estimated using seven- or 12-gene signature