Tag: Genetics
Study Looks at Clonal Hematopoiesis in Pediatric Cancer Survivors
Clonal hematopoiesis occurs more often in pediatric cancer survivors; is associated with exposures to alkylating agents, radiation, bleomycin
Genetic, Environmental Prenatal Risk Factors Play Role in Early Atopic Dermatitis
Nonmodifiable risk factors include gestational diabetes, maternal history of allergy, prenatal history of eczema
Risk for Contralateral Breast Cancer Higher for Certain Pathogenic Variant Carriers
Women with germline PVs in BRCA1, BRCA2, CHEK2, and PALB2 have elevated risk for contralateral breast cancer
Precision Medicine Can Be Integrated Into Routine Cancer Care
Implementation of precision oncology recommendations has clinical utility for patients with gastrointestinal cancers
Genetic, Lifestyle Factors Independently Linked to IBD Risk
For those with high genetic risk, hazard ratios were reduced nearly by half for favorable lifestyle versus unfavorable lifestyle
Healthy Lifestyle Lowers Memory Decline, Even for Those With Genetic Risk
APOE ε4 carriers with favorable or average lifestyles showed slower memory decline than those with unfavorable lifestyles
Risk for SIDS Increased for Infants With Sibling Who Died of SIDS
Siblings have about fourfold higher rate of SIDS compared with the general population after adjustment for sex, age, calendar year
Prevalence of VEXAS Syndrome Identified in U.S. Health System
Disease-causing UBA1 variants identified in one in 4,269 men older than 50 years and one in 26,238 women older than 50 years
First-Degree Relatives Have High Perceived Risk for Rheumatoid Arthritis
Relationship with index patient, high health anxiety, female gender, high perceived concern about RA linked to increased FDR perceived risk
2022 ICC Recategorization Facilitates Risk Stratification of Myelodysplastic Syndrome
Distinct mutational landscape and poorer outcomes seen for patients with MDS/acute myeloid leukemia versus MDS not otherwise specified
