Tag: Genetics
Certain Risk Factors for MS Linked to Pediatric Brain Volume
MS-polygenic risk score and household parental smoking negatively linked to total brain volume, thalamic volume
SABCS: Risk-Reducing Surgery Improves Outcomes in Young Breast Cancer Patients With BRCA Mutations
Findings show survival benefits for both risk-reducing mastectomy and salpingo-oophorectomy
Early Bilateral Oophorectomy Increases Risk of Alzheimer Disease
Risk even higher among women with bilateral oophorectomy carrying an APOE4 allele
Model Including Polygenic Risk, Polysocial Score Improves CHD Risk Prediction
Polygenic risk score and polysocial score have independent and additive effects on coronary heart disease
Neoantigen DNA Vaccines Safe, Induce Response in Triple-Negative Breast Cancer
Fourteen of 18 patients had neoantigen-specific T-cell responses; recurrence-free survival was 87.5 percent at 36 months
Potential Genetic Link ID’d Between Thyroid Disease, Alopecia Areata
Significant genetic predictions of alopecia seen with hypothyroidism, Hashimoto thyroiditis, and subacute thyroiditis
Multigene Signature Can Help Tailor Chemo for Operable Triple-Negative Breast Cancer
Improved three-year disease-free and recurrence-free survival seen with intensive chemotherapy regimen
Genome Sequencing Feasible for Newborn Screening
Authors say sequencing could expand range of treatable conditions screened in newborns
Researchers Find Biomarker Tied to Severity of Ulcerative Colitis
HLA-DRB1*01:03 allele linked to severe disease requiring hospitalization, major operation, systemic corticosteroid use
