Tag: Genetics
Circulating Tumor DNA Can ID Outcomes for Patients With Melanoma
ctDNA detection at baseline was associated with worse recurrence-free, overall survival in BRAFV600-mutant stage III melanoma
Link Between Global β-Amyloid, Tau Deposition Varies by Sex
Women and those with paternal history of Alzheimer disease have stronger association between Aβ, tau deposition than men or those with maternal history
Prostate Cancer Screening Program Beneficial in Top Decile of Polygenic Risk Score
Targeted screening to participants in ≥90th percentile of polygenic risk score results in detection of cancer warranting clinical management in 55.1 percent
Minimal TV Viewing May Cut ASCVD Risk in Those With T2DM Genetic Risk
Medium and high T2DM genetic risk not linked to increased risk for ASCVD when TV viewing is no more than one hour/day
Mutational Signatures Tied to Haloalkane Exposure Are Enriched in Firefighters
Researchers say identifying occupational correlates with variants associated with exposure to haloalkanes may help pinpoint avoidable occupational hazards
Ultra-Rapid Molecular-Genetic Assays Feasible for Tumor Classification During Surgery
Ultra-rapid digital droplet PCR can measure the levels of tumor cells in a tissue sample in about 15 minutes
Sisters of Those With Adverse Pregnancy Outcome Also Have Increased CVD Risk
Women with APO and their APO-free sisters both have increased risks relative to unrelated APO-free comparators
Ethnoracial Disparities Seen in Access to Genetic Testing in Pediatric Neurology
White pediatric neurology patients more likely to have completed one or more genetic test than Black patients
No Evidence Found Linking Sickle Cell Trait With Unexplained Sudden Death
No evidence supports physical exertion without rhabdomyolysis or heat injury causing sudden death in sickle cell trait
Rheumatoid Arthritis Causally Linked to Prostate Cancer
No significant associations seen for SLE or AS with prostate cancer or in reverse MR analyses
