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A considerable proportion of patients with severe acute respiratory syndrome coronavirus 2 have gastrointestinal manifestations

GI Manifestations Seen for Nearly One in Three With SARS-CoV-2

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Significant portion have diarrhea, nausea, vomiting, and/or abdominal discomfort before respiratory symptoms
Mindfulness-based stress reduction training is associated with robust improvements in gastrointestinal symptoms for patients with irritable bowel syndrome

Mindfulness-Based Stress Reduction May Cut IBS Symptoms

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Increased ability to retain present-moment focus and to act with awareness tied to symptom improvement
In a document issued by the American Gastroenterological Association

Recommendations Issued for GI Procedures During COVID-19

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N95 masks recommended instead of surgical masks for GI procedures; double gloves recommended
Gastrointestinal symptoms are common in patients with coronavirus disease 2019

Gastrointestinal Symptoms Common in COVID-19 Patients

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GI symptoms were more prevalent in later stages of epidemic in China
Endoscopy within six hours versus six to 24 hours after consultation is not associated with lower 30-day mortality in patients with acute upper gastrointestinal bleeding who are at high risk for further bleeding or death

Endoscopy Within Six Hours Does Not Lower Mortality in GI Bleed

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30-day mortality did not differ for those undergoing endoscopy within six hours versus six to 24 hours
Patients with mild coronavirus disease 2019 can present with digestive symptoms

Patients With Mild COVID-19 May Present With Digestive Symptoms

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Many with digestive symptoms present with diarrhea; 62.4 percent with digestive symptoms have fever
The U.S. Food and Drug Administration issued a MedWatch Safety Alert on Tuesday about the potential risk for SARS-CoV-2 transmission with the use of fecal microbiota for transplantation to treat Clostridioides difficile infection.

FDA Issues Safety Alert for COVID-19 Risk With Fecal Transplant

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Studies have recently shown SARS-CoV-2 present in stool of infected patients, suggesting transmission risk
In a special article published online March 17 in Clinical Gastroenterology and Hepatology

Information on COVID-19 Provided for Gastroenterologists

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COVID-19 can include GI symptoms such as diarrhea; gastrointestinal tract is potential route of infection
Patients with coronavirus 2019 frequently have digestive symptoms

Digestive Symptoms Reported for About Half of COVID-19 Patients

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Likelihood of being cured, discharged higher for patients without versus with digestive symptoms
There is evidence for gastrointestinal infection of SARS-CoV-2

Evidence Points to GI Infection by SARS-CoV-2

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Viral host receptor ACE2 stained positive mainly in cytoplasm of gastrointestinal epithelial cells