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Proton pump inhibitor use is associated with increased risk of hip fracture among dialysis patients

Proton Pump Inhibitor Use Tied to Hip Fracture in Dialysis Patients

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Correlation between PPI and hip fracture persisted for subgroups with low, medium, high PPI use
Fifteen genetic determinants of fracture

Fifteen Genetic Determinants of Fracture Identified

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All determinants also associated with bone mineral density, which showed causal effect on fracture
Postoperative mortality is lower for medically stable older patients who undergo surgery for hip fracture on the day of admission or the following day

Lower Post-Op Mortality With Hip Fx Surgery on Day of Admission

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Additional 10.9 deaths per 1,000 surgeries projected if all surgeries done after inpatient day three
For older patients undergoing hip fracture repair

Sedation Level Doesn’t Impact Delirium Risk After Hip Fx Repair

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In subgroup analysis, heavier versus lighter sedation doubled risk of delirium in low comorbid states
Only one-third of Canadian patients received hip fracture repair surgery within the desired 24 hours

One-Third of Canadian Patients Get Hip Fx Repair Within 24 Hours

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Hospital factors have a larger impact on delays than physician factors
Cervical spine injuries occur less frequently among motorcycle crash victims who were wearing a helmet versus those not wearing a helmet at the time of injury

Fewer Cervical Spine Injuries Seen With Motorcycle Helmet Use

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Findings based on analysis of motorcycle accident victims by helmet use
Obesity is associated with worse outcomes in skilled nursing facility residents receiving post-acute care for hip fracture

Obesity Worsens Skilled Nursing Facility Outcomes After Hip Fx

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Findings among Medicare beneficiaries receiving post-acute care for hip fracture
In recent years there have been low rates of osteoporosis treatment initiation after a hip fracture

Drop in Osteoporosis Treatment Initiation After Hip Fracture

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Adherence to regimen needed to cut subsequent fracture risk
Empagliflozin does not increase the risk of bone fracture in patients with type 2 diabetes

Empagliflozin Doesn’t Up Risk of Bone Fractures

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Per pooled data from placebo-controlled trials and data from a head-to-head study with glimepiride
The U.S. Preventive Services Task Force recommends screening for osteoporosis to prevent fractures for women aged ≥65 years and for postmenopausal women aged <65 years at increased risk of osteoporosis. These findings form the basis of a final recommendation statement published online June 26 in the Journal of the American Medical Association.

USPSTF Favors Osteoporosis Screening to Prevent Fracture

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Screening with bone measurement recommended for women aged ≥65, younger women at risk