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AAP Issues Guideline for Managing Young Infants With Fever

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Recommendations address evaluation, management of fever in infants aged 8 to 21, 22 to 28, 29 to 60 days; role of parents emphasized

Methylprednisolone Added to IVIG May Cut Fever in MIS-C

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IV immunoglobulins plus methylprednisolone associated with lower risk for treatment failure compared with immunoglobulins alone

Young children experiencing an initial vaccine-proximate febrile seizure do not have increased risk of developmental or behavioral problems

Post-Vaxx Febrile Seizures Not Linked to Child Development Outcomes

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Risk of developmental, behavioral problems not up in young children with febrile seizures after vaccination
A considerable proportion of patients with severe acute respiratory syndrome coronavirus 2 have gastrointestinal manifestations

GI Manifestations Seen for Nearly One in Three With SARS-CoV-2

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Significant portion have diarrhea, nausea, vomiting, and/or abdominal discomfort before respiratory symptoms
A new strain of Streptococcus pyogenes is causing scarlet fever

New Strain of S. pyogenes Causing Scarlet Fever in U.K.

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New, more toxigenic strain may explain recent increase in scarlet fever activity in England
A new prediction rule can accurately identify febrile infants aged ≤60 days at low risk for serious bacterial infections using urinalysis

Prediction Rule IDs Febrile Infants 0 to 2 Months Old at Low Risk for...

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Rule relies on clinical information, absolute neutrophil count, procalcitonin, urinalysis results
Acetaminophen can reduce the risk for febrile seizure recurrence during the same fever episode among infants and children

Acetaminophen Can Reduce Recurrence of Febrile Seizures

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For children, infants with febrile seizure, recurrence down with acetaminophen versus no antipyretic
For febrile infants

Human Rhinovirus Commonly Detected in Febrile Infants

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HRV presence does not alter risk of UTI; 29 to 90 day olds with HRV less likely to have bacterial infection
The 2011 clinical practice guideline on urinary tract infection in young children has been reaffirmed

Clinical Practice Guideline on UTI in Febrile Young Reaffirmed

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2011 CPG on urinary tract infection in infants and young children reaffirmed after review of literature
Clinicians should suspect coccidioidomycosis

Clinicians Should Consider Valley Fever in Some Flu Patients

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Endemic in desert regions in southwest U.S. and some areas in Central and South America