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Valproic acid and topiramate are confirmed teratogens

Study Confirms Teratogenicity of Valproic Acid, Topiramate

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Eight specific types of major congenital malformations associated with prenatal exposure to valproic acid
Laser interstitial thermal therapy targeting greater amygdala volume is more likely to be associated with Engel I outcomes for mesial temporal lobe epilepsy

Targeted Laser Surgery Treats Temporal Lobe Epilepsy

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Engel I outcomes more likely with ablations targeting specific lobe structures
Antiepileptic drug use is not significantly associated with dementia risk in patients in Germany

Antiepileptic Drugs Not Tied to Dementia Risk

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No increased overall risk found, but levetiracetam generic brands tied to higher dementia risk
The robotic stereoelectroencephalography procedure to determine whether patients with pharmacoresistant epilepsy are candidates for brain surgery is safer and more efficient and more often leads to favorable epilepsy outcomes than the traditional subdural electrode implantation method among those undergoing resection or ablation

Less Invasive Method Safely IDs Epilepsy Surgical Candidates

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Stereoelectroencephalography has better outcomes than subdural electrode implants in some cases
The first generic version of Sabril (vigabatrin) has been approved by the U.S. Food and Drug Administration to prevent complex partial seizures in adults and children aged 10 years and older with epilepsy.

FDA Approves First Generic Version of Epilepsy Drug Sabril

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Generic equivalents held to same vigorous manufacturing standards as brand-name drugs
Use of the antiepileptic drug valproate during pregnancy is associated with an increased risk for attention-deficit/hyperactivity disorder among offspring

Prenatal Valproate Exposure Linked to Increased ADHD Risk

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Maternal use of other antiepileptic drugs not tied to increased ADHD risk
The risk for sudden unexpected death in epilepsy may decrease over time

Risk of Sudden Death in Epilepsy Can Decline Over Time

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Those with a low risk for SUDEP generally remain in this categorization during three years of tracking
The interpretation of genomic epilepsy tests has evolved rapidly in the last five years

Results of Pediatric Genomic Epilepsy Tests Often Reclassified

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Over 30 percent of pediatric patients with genetic dx, undiagnosed conditions had results reclassified
The first cannabis-based medication approved by the U.S. Food and Drug Administration is now available by prescription nationwide.

First FDA-Approved Cannabis Drug Now Available in U.S.

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Epidiolex is a twice-daily oral solution for use in patients with two types of epileptic syndromes
Potentially modifiable risk factors in midlife are associated with the risk of developing late-onset epilepsy

Modifiable Midlife Risk Factors Linked to Late-Onset Epilepsy

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Baseline hypertension, diabetes, smoking, apolipoprotein E ε4 genotype linked to increased risk