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The interpretation of genomic epilepsy tests has evolved rapidly in the last five years

Results of Pediatric Genomic Epilepsy Tests Often Reclassified

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Over 30 percent of pediatric patients with genetic dx, undiagnosed conditions had results reclassified
The first cannabis-based medication approved by the U.S. Food and Drug Administration is now available by prescription nationwide.

First FDA-Approved Cannabis Drug Now Available in U.S.

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Epidiolex is a twice-daily oral solution for use in patients with two types of epileptic syndromes
Potentially modifiable risk factors in midlife are associated with the risk of developing late-onset epilepsy

Modifiable Midlife Risk Factors Linked to Late-Onset Epilepsy

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Baseline hypertension, diabetes, smoking, apolipoprotein E ε4 genotype linked to increased risk
Next-generation sequencing can improve treatment efficacy and reduce hospitalization in children with drug-resistant epilepsy

Next-Generation Sequencing May Improve Pediatric Epilepsy Tx

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In children with drug-resistant epilepsy, NGS can help establish diagnosis, improve treatment efficacy
The U.S. Food and Drug Administration has approved Epidiolex oral solution for treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome for patients age 2 years and older.

FDA Approves Epidiolex for Severe Forms of Epilepsy

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Cannabidiol oral solution approved for patients 2 and older with Lennox-Gastaut and Dravet syndromes
Women with epilepsy and no history of infertility have a similar likelihood of achieving pregnancy as peers without epilepsy

Epilepsy Does Not Appear to Affect Likelihood of Pregnancy

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Likelihood of achieving pregnancy, time to pregnancy similar in women with, without epilepsy
Although most adults with epilepsy report taking epilepsy medication

Too Few Adults Taking Epilepsy Meds Have Seizure Control

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Ninety percent of those with active epilepsy take meds; 44 percent of those report seizure control
The risk of unnatural death is increased among people with epilepsy

Increased Risk of Unnatural Death in People With Epilepsy

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Increased likelihood of dying of unnatural cause, unintentional injury or poisoning, or suicide
Early-life epilepsy should be treated with the same urgency as pediatric cancer

Early-Life Epilepsy Should Be Urgently Treated With EBM

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Best diagnostics and evidence-based treatments should be used from the start of the disease
Exposure to sodium valproate or a combination of antiepileptic drugs in utero is associated with worse attainment on national educational tests for 7-year-olds

Educational Attainment Down With In Utero Exposure to AEDs

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Exposure to sodium valproate, combo of antiepileptic drugs tied to worse attainment on national tests