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Tag: Epilepsy

Limited evidence suggests that self-management strategies modestly improve some outcomes among persons with epilepsy

Self-Management Strategies Offer Limited Benefit in Epilepsy

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Education-based approaches improve self-management behavior; psychosocial therapy approaches up QoL
Sudden unexpected death in epilepsy can occur across the full spectrum of epilepsies

Sudden Death Can Occur in Full Spectrum of Epilepsies

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Only 37 percent of patients with sudden unexpected death in epilepsy took last dose of antiseizure meds
There is an increased risk for behavioral problems in children of mothers with epilepsy who take common antiepileptic drugs during pregnancy

Prenatal Antiepileptic Rx Exposure Ups Risk for Behavioral Issues

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Findings seen among Dutch children exposed to one of four common antiepileptic drugs in utero
Valproic acid and topiramate are confirmed teratogens

Study Confirms Teratogenicity of Valproic Acid, Topiramate

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Eight specific types of major congenital malformations associated with prenatal exposure to valproic acid
Laser interstitial thermal therapy targeting greater amygdala volume is more likely to be associated with Engel I outcomes for mesial temporal lobe epilepsy

Targeted Laser Surgery Treats Temporal Lobe Epilepsy

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Engel I outcomes more likely with ablations targeting specific lobe structures
Antiepileptic drug use is not significantly associated with dementia risk in patients in Germany

Antiepileptic Drugs Not Tied to Dementia Risk

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No increased overall risk found, but levetiracetam generic brands tied to higher dementia risk
The robotic stereoelectroencephalography procedure to determine whether patients with pharmacoresistant epilepsy are candidates for brain surgery is safer and more efficient and more often leads to favorable epilepsy outcomes than the traditional subdural electrode implantation method among those undergoing resection or ablation

Less Invasive Method Safely IDs Epilepsy Surgical Candidates

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Stereoelectroencephalography has better outcomes than subdural electrode implants in some cases
The first generic version of Sabril (vigabatrin) has been approved by the U.S. Food and Drug Administration to prevent complex partial seizures in adults and children aged 10 years and older with epilepsy.

FDA Approves First Generic Version of Epilepsy Drug Sabril

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Generic equivalents held to same vigorous manufacturing standards as brand-name drugs
Use of the antiepileptic drug valproate during pregnancy is associated with an increased risk for attention-deficit/hyperactivity disorder among offspring

Prenatal Valproate Exposure Linked to Increased ADHD Risk

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Maternal use of other antiepileptic drugs not tied to increased ADHD risk
The risk for sudden unexpected death in epilepsy may decrease over time

Risk of Sudden Death in Epilepsy Can Decline Over Time

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Those with a low risk for SUDEP generally remain in this categorization during three years of tracking