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Tag: Epilepsy

For children exposed to antiepileptic drugs in utero

Folic Acid Lessens Autism Risk for Fetal Anti-Epileptic Exposure

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For children exposed to antiepileptic drugs in utero, risk may be mitigated by folic acid supplementation
More than one-third of patients with newly diagnosed epilepsy do not respond to treatment with antiepileptic drugs

More Than a Third of Patients Do Not Respond to Antiepileptics

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Overall, 89.9 percent of patients who achieve seizure control do so with first, second AED regimen
Non-pharmaceutical therapies may offer seizure relief for children with epilepsy

Non-Drug Options Provide Seizure Relief in Children

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And, slow initiation of the ketogenic diet shows good outcomes in children with epilepsy
For pediatric patients with drug-resistant epilepsy

Surgery Reduces Seizures in Drug-Resistant Epilepsy

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And most common diagnoses based on resected brain specimens include hippocampal sclerosis, tumors
Patients with epilepsy undergoing medial temporal lobe surgery have increased prevalence of tinnitus compared with controls and participants with self-reported epilepsy

Medial Temporal Lobe Surgery Linked to Prevalence of Tinnitus

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Increased prevalence of tinnitus compared with controls and participants with self-reported epilepsy
Women on antiepileptic drugs during pregnancy for epilepsy or other indications are at increased risk of giving birth to premature and small-for-gestational-age infants

Risk of Prematurity, SGA Up for Women on Antiepileptic Drugs

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Increased risk for women on AEDs for epilepsy or other indications; risk varies with drug used
In 2015

Rates of Active, Current Epilepsy in U.S. Adults Rising

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Variation in estimated number of people with active epilepsy, from 5,900 in Wyoming to 427,700 in Calif.
For patients with super-refractory status epilepticus

Brexanolone Tolerated in Super-Refractory Status Epilepticus

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Associated with high rate of third-line agent weaning; no serious adverse events attributed to the drug
Several significant interactions can occur between cannabidiol and antiepileptic drugs

Interactions Occur With Cannabidiol, Antiepileptic Drugs

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Most observed mean level changes fall within accepted therapeutic range
Genetic investigation emphasizing sequencing tests should be incorporated into the routine initial evaluation of young children with epilepsy

Research Supports Genetic Testing in Early Life Epilepsy

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Faster diagnosis leads to faster treatment, researcher says