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Depression treatment with venlafaxine is associated with increased levels of the bone resorption marker C-terminal cross-linking telopeptide of type 1 collagen

Venlafaxine Use Linked to Bone Turnover Markers in Older Adults

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Increase in CTX and decrease in P1NP, consistent with accelerated bone loss with antidepressant tx
In a case report published online April 30 in Clinical & Experimental Ophthalmology

Venlafaxine-Induced Rise in Intraocular Pressure Described

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Case report of male patient with chronic open angle glaucoma starting venlafaxine for depression