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Guidelines have been developed for the management of severe atopic dermatitis; the recommendations have been published as a clinical management review in the January issue of The Journal of Allergy and Clinical Immunology: In Practice.

Guidelines Developed for Managing Severe Atopic Dermatitis

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Management is generally in a stepwise manner, including moisturizers and avoiding triggers
Topical application of a transient receptor potential vanilloid subfamily

Investigational Cream Promising for Atopic Dermatitis

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In phase IIb trial, success rates were higher with TRPV1 antagonist than with vehicle cream
The mean cumulative lifetime prevalence of atopic eczema is 9.9 percent

Mean Cumulative Lifetime Prevalence of Eczema 9.9 Percent

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Highest rates of active disease seen for children aged 0 to 17 years and older adults aged 75 to 99
The prevalence of atopic dermatitis is 7.3 percent among U.S. adults

Prevalence of Atopic Dermatitis 7.3 Percent in U.S. Adults

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Patients with AD and more severe disease have higher scores on dermatology life quality index
Physicians can create an adherence protocol for patients

Doctors Can Help Children, Teens Adhere to Eczema Treatment Plan

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Aids include simplifying treatment, creating reminders, sharing success stories
Atopic dermatitis dramatically impacts the quality of life of patients

Atopic Dermatitis Places Heavy Burden on Patients

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Overall and mental health, life satisfaction all impacted, especially for moderate, severe disease
Patients with moderate/severe atopic dermatitis have higher patient-reported burden than those with mild atopic dermatitis

High Patient Burden With Moderate-to-Severe Atopic Dermatitis

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Many patients with moderate/severe atopic dermatitis have inadequate disease control
Adults with severe atopic eczema are at increased risk of cardiovascular disease

Severe Atopic Eczema Tied to Higher CV Disease Risk

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Risk of cardiovascular outcomes was greatest for those with the most active atopic eczema
For children with eczema

No Clinical Benefit Seen for Bath Emollients in Childhood Eczema

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POEM scores didn't meet minimal clinically important difference after adjustment for confounders
In patients with atopic dermatitis and birch pollen allergy

Birch Pollen-Related Foods Can Trigger Dermatitis Reactions

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Intake may lead to aggravation of symptoms in patients with atopic dermatitis, birch pollen allergy