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In the eastern United States

Opioid-Related Mortality Up From 1999 to 2016 in Eastern U.S.

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Opioid-related mortality rates, especially from synthetic opioids, increased rapidly in eastern states
Since the early 2000s

Since Early 2000s, Overdose Death Rates Are Highest in U.S.

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U.S. was not an outlier in terms of drug overdose mortality prior to the early 2000s
A substantial proportion of heterosexual syphilis transmission seems to be occurring among those who use drugs

CDC: Heterosexual Syphilis Transmission Up for Drug Users

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Substantial proportion of heterosexual syphilis transmission seen in drug users, especially meth users
Misuse of prescribed opioids is associated with other high-risk drug behaviors

Misuse of Rx Opioids Linked to Other High-Risk Behaviors

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Prescribed opioid misuse strongly tied to other drug use disorders, illegal activity, psychological distress
The percentage of donors from whom hearts were recovered for transplantation who died from drug intoxication increased from 1999 to 2016

Donor Heart Recovery From Drug-Intoxicated Deaths Has Increased

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Campaigns promoting organ donation in populations affected by drugs have contributed to increase
Mandated neonatal abstinence syndrome surveillance and reporting allows state health departments to quantify incidence and informs programs and services

Mandated Neonatal Abstinence Reporting Helps Quantify Cases

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Five of six states with mandatory reporting receive case reports within 30 days of diagnosis
For the first time in history

Opioids Now More Deadly for Americans Than Traffic Accidents

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Preventable injuries are the third leading cause of death in the United States
The Substance Abuse and Mental Health Services Administration national helpline (800-662-HELP) seems to be underappreciated in the media and by the general population

800-662-HELP Underappreciated in Media, General Population

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Searches for SAMHSA hotline did not increase after singer Demi Lovato's heroin-related overdose
Among persons who inject drugs

Nine Cases of Wound Botulism ID’d in Injection Drug Users

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All patients used injection drugs; seven reported using black tar heroin and six practiced skin popping
Specialized smartphone software can be used to detect early signs of opioid overdose

Smartphone App Can Detect Early Signs of Opioid Overdose

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App has high sensitivity, specificity for opioid-induced central apnea, respiratory depression